SCHEMBL926429

SCHEMBL926429

CCO[Si](OCC)(OCC)C(C)c1ccc(C(Cl)(Cl)Cl)cc1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TSHR P16473 2/20 0.31
ATM Q13315 1/20 0.31
GPR35 Q9HC97 1/20 0.31
RORC P51449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574403 0.85 ESR1 (0.33) LMNA
SCHEMBL929186 0.80 TSHR (0.31) TSHRATM
SCHEMBL926681 0.80 TSHR (0.33) TSHRATM
SCHEMBL27135638 0.80 PTGS2 (0.36) LMNA
SCHEMBL3397079 0.78 CHRNA7 (0.34) LMNASMN1; SMN2
SCHEMBL28418566 0.78 ESR1 (0.47) LMNATSHR
SCHEMBL926926 0.77 TSHR (0.32) TSHRATM
SCHEMBL927433 0.77 LMNA (0.31) LMNA
SCHEMBL927589 0.77 LMNA (0.32) LMNA
SCHEMBL928450 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121349-B1 RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2010-11-17 EP claimed
EP-2207782-A2 HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM Momentive Performance Materials Inc. (US) 2010-07-21 EP claimed
US-7625965-B2 Rubber composition, process of preparing same and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-12-01 US claimed
EP-2121349-A1 RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM Momentive Performance Materials Inc. (US) 2009-11-25 EP claimed
WO-2009058373-A2 HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-05-07 WO claimed
US-20090111923-A1 Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom MOMENTIVE PERFORMANCE MATERIALS INC. 2009-04-30 US claimed
WO-2008097587-A1 RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC (US) 2008-08-14 WO claimed
US-20080194746-A1 Rubber composition, process of preparing same and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. 2008-08-14 US claimed
EP-2708546-B1 Halo-Functional Silane, process for its preparation, rubber composition containing same and articles manufactured therefrom MOMENTIVE PERFORMANCE MAT INC (US) 2016-01-06 EP disclosed
EP-2708546-A1 Halo-Functional Silane, process for its preparation, rubber composition containing same and articles manufactured therefrom Momentive Performance Materials Inc. (US) 2014-03-19 EP disclosed
EP-2207782-B1 HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2014-02-26 EP disclosed
US-8372906-B2 Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-02-12 US disclosed
CN-102432924-A Rubber composition, method of making the same, and articles made therefrom MOMENTIVE PERFORMANCE MAT INC 2012-05-02 CN disclosed
US-20110003922-A1 Halo-Functional Silane, Process For Its Preparation, Rubber Composition Containing Same and Articles Manufactured Therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-01-06 US disclosed
US-7816435-B2 Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-10-19 US disclosed
EP-2207782-A2 HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM Momentive Performance Materials Inc. (US) 2010-07-21 EP disclosed
US-7625965-B2 Rubber composition, process of preparing same and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-12-01 US disclosed
WO-2009058373-A2 HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-05-07 WO disclosed
US-20090111923-A1 Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom MOMENTIVE PERFORMANCE MATERIALS INC. 2009-04-30 US disclosed
US-20080194746-A1 Rubber composition, process of preparing same and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. 2008-08-14 US disclosed