SCHEMBL8416657

SCHEMBL8416657

CCCCCCCCCCCCCCCCN(C(C)CO)C(C)CO

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.43
DNM1 Q05193 4/20 0.42
TSHR P16473 2/20 0.40
ALDH1A1 P00352 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
CYP2D6 P10635 2/20 0.36
GBA1 P04062 1/20 0.36
SPHK1 Q9NYA1 1/20 0.36
GMNN O75496 1/20 0.36
POLB P06746 1/20 0.36
THPO P40225 1/20 0.36
MTOR P42345 1/20 0.36
BLM P54132 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8415648 1.00 LMNA (0.43) LMNADNM1TSHRALDH1A1HSD17B10
SCHEMBL8415519 1.00 LMNA (0.43) LMNADNM1TSHRALDH1A1HSD17B10
SCHEMBL8415645 1.00 LMNA (0.43) LMNADNM1TSHRALDH1A1HSD17B10
SCHEMBL8415512 0.89 EPHX2 (0.46) LMNAALDH1A1MEN1KMT2ACYP2D6
SCHEMBL11469170 0.83 LMNA (0.42) LMNADNM1TSHRALDH1A1HSD17B10
SCHEMBL8749793 0.82 LMNA (0.43) LMNADNM1TSHRALDH1A1HSD17B10
SCHEMBL9807812 0.81 DNM1 (0.46) DNM1TSHRCA12CA1CA2
SCHEMBL9807757 0.81 DNM1 (0.46) DNM1TSHRCA12CA1CA2
Hydrochloric Acid SCHEMBL28495694 0.80 DNM1 (0.44) LMNADNM1TSHRALDH1A1HSD17B10
SCHEMBL17782133 0.79 DNM1 (0.44) LMNADNM1TSHRCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0686663-B1 Process for crystal nucleation of crystalline thermoplastic resin and crystalline thermoplastic resin composition MITSUI CHEMICALS INC (JP) 1999-12-22 EP disclosed
EP-0931805-A1 TRIBLOCK OLIGOMERS, THERMOPLASTIC RESIN COMPOSITIONS, AND ANTIFOG MOLDINGS Mitsui Chemicals, Inc. (JP) 1999-07-28 EP disclosed
US-5856386-A ROSIN ACID METALLIC SALT MITSUI PETROCHEMICALS INDUSTRIES, LTD. (JP) 1999-01-05 US disclosed
EP-0879855-A1 THERMOPLASTIC RESIN COMPOSITION AND FILM MADE FROM THE COMPOSITION Mitsui Chemicals, Inc. (JP) 1998-11-25 EP disclosed
EP-0686663-A1 Process for crystal nucleation of crystalline thermoplastic resin and crystalline thermoplastic resin composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-12-13 EP disclosed