SCHEMBL8416668

SCHEMBL8416668

Nc1c(I)c(N)c(I)c(C(O)CO)c1I.O=C(CO)Nc1c(I)c(NC(=O)CO)c(I)c(C(O)CO)c1I

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7592516 0.91 LMNA (0.35) LMNASMN1; SMN2
SCHEMBL8562051 0.81 LMNA (0.46) LMNA
SCHEMBL7589511 0.79
SCHEMBL6251970 0.76
SCHEMBL6224131 0.74
SCHEMBL6252055 0.74
SCHEMBL7595391 0.73 LMNA (0.51) LMNASMN1; SMN2
SCHEMBL6253824 0.69
SCHEMBL7595489 0.69 LMNA (0.34) LMNASMN1; SMN2
SCHEMBL8377087 0.68 LMNA (0.32) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0782564-B1 IODINATED X-RAY CONTRAST MEDIA NYCOMED IMAGING AS (NO) 1999-09-01 EP disclosed