SCHEMBL8416688

SCHEMBL8416688

CC(Oc1ccccc1)(Oc1ccccc1)C([SiH3])(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.39
LTA4H P09960 3/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.34
RIPK1 Q13546 1/20 0.33
PPARG P37231 4/20 0.33
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
ATM Q13315 1/20 0.32
PPARA Q07869 2/20 0.31
KCNA3 P22001 1/20 0.31
CYP2D6 P10635 2/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
CA5A P35218 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8903226 0.73 CA4 (0.39) CA4LTA4HTSHRMAPK1RIPK1
SCHEMBL1660600 0.72 CA4 (0.48) CA4LTA4HTSHRMAPK1RIPK1
SCHEMBL10405698 0.72 CA4 (0.48) CA4LTA4HTSHRMAPK1RIPK1
SCHEMBL188025 0.72 LTA4H (0.45) CA4LTA4HTSHRALDH1A1ALOX15
SCHEMBL93074 0.72 CA4 (0.48) CA4LTA4HTSHRMAPK1RIPK1
SCHEMBL4224012 0.72 CA4 (0.48) CA4LTA4HTSHRMAPK1RIPK1
SCHEMBL3851931 0.71 CA4 (0.42) CA4LTA4HTSHRMAPK1RIPK1
SCHEMBL6047052 0.70 CA4 (0.46) CA4LTA4HTSHRMAPK1RIPK1
SCHEMBL10592534 0.70 CA4 (0.46) CA4LTA4HTSHRMAPK1RIPK1
Phosphine SCHEMBL20897416 0.70 CA4 (0.46) CA4LTA4HTSHRMAPK1RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1195708-C Manufacture of formed refractory products JAPAN CASTING TECHNOLOGY CONSU (JP) 2005-04-06 CN disclosed
CN-1116943-C Method for making formed refractory casting mould with core installed JAPAN CASTING TECHNOLOGY CONSU (JP) 2003-08-06 CN disclosed
CN-1067358-C Binder for refractory molded article JAPAN CASTING TECHNOLOGY CONSU (JP) 2001-06-20 CN disclosed
CN-1289655-A Method for making formed refractory casting mould with core installed JAPAN CASTING TECHNOLOGY CONSU (JP) 2001-04-04 CN disclosed
CN-1289739-A Manufacture of formed refractory products JAPAN CASTING TECHNOLOGY CONSU (JP) 2001-04-04 CN disclosed
EP-0661246-B1 Process for preparing refractory molded articles and binders therefor CADIC CORP (JP) 1999-09-01 EP disclosed
US-5611848-A Process for preparing refractory molded articles and binders therefor CADIC CORPORATION (JP) 1997-03-18 US disclosed
US-5569320-A ORNAMENTS, MOLDS OR A CORE CADIC CORPORATION (JP) 1996-10-29 US disclosed
EP-0661246-A1 Process for preparing refractory molded articles and binders therefor CADIC CORPORATION (JP) 1995-07-05 EP disclosed