SCHEMBL8903226

SCHEMBL8903226

CC([SiH3])(Oc1ccccc1)C(Oc1ccccc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.39
RIPK1 Q13546 1/20 0.37
LTA4H P09960 2/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.34
PPARG P37231 4/20 0.34
PPARA Q07869 3/20 0.34
CYP2D6 P10635 2/20 0.33
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KCNA3 P22001 1/20 0.31
RORC P51449 1/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11580065 0.78 CA4 (0.43) CA4RIPK1LTA4HTSHRMAPK1
SCHEMBL8416688 0.73 CA4 (0.39) CA4RIPK1LTA4HTSHRMAPK1
SCHEMBL1660600 0.72 CA4 (0.48) CA4RIPK1LTA4HTSHRMAPK1
SCHEMBL10405698 0.72 CA4 (0.48) CA4RIPK1LTA4HTSHRMAPK1
SCHEMBL93074 0.72 CA4 (0.48) CA4RIPK1LTA4HTSHRMAPK1
SCHEMBL188025 0.72 LTA4H (0.45) CA4LTA4HTSHRALDH1A1ALOX15
SCHEMBL4224012 0.72 CA4 (0.48) CA4RIPK1LTA4HTSHRMAPK1
SCHEMBL3851931 0.71 CA4 (0.42) CA4RIPK1LTA4HTSHRMAPK1
SCHEMBL6047052 0.70 CA4 (0.46) CA4RIPK1LTA4HTSHRMAPK1
Phosphine SCHEMBL20897416 0.70 CA4 (0.46) CA4RIPK1LTA4HTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5611848-A Process for preparing refractory molded articles and binders therefor CADIC CORPORATION (JP) 1997-03-18 US disclosed