Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.48 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415851 | 0.94 | GRM2 (0.41) | ALOX5TLR2EPHX2FAAH | |
| SCHEMBL8416769 | 0.94 | GRM2 (0.41) | ALOX5TLR2EPHX2FAAH | |
| SCHEMBL8416773 | 0.94 | GRM2 (0.41) | ALOX5TLR2EPHX2FAAH | |
| SCHEMBL8415827 | 0.94 | GRM2 (0.41) | ALOX5TLR2EPHX2FAAH | |
| SCHEMBL8415832 | 0.94 | GRM2 (0.41) | ALOX5TLR2EPHX2FAAH | |
| SCHEMBL8415858 | 0.93 | GRM2 (0.41) | ALOX5TLR2EPHX2FAAH | |
| SCHEMBL8415854 | 0.93 | GRM2 (0.41) | ALOX5TLR2EPHX2FAAH | |
| SCHEMBL8417247 | 0.88 | GRM2 (0.43) | TLR2EPHX2FAAH | |
| SCHEMBL8417241 | 0.88 | GRM2 (0.43) | TLR2EPHX2FAAH | |
| SCHEMBL8416786 | 0.81 | ALOX5 (0.43) | ALOX5TLR2EPHX2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990326-A | AN ANTIINFLAMMATORY AGENT AS INHIBITORS OF LEUKOTRIENE HYDROLASE | G.D. SEARLE & CO. (US) | 1999-11-23 | — | — | US | disclosed |
| EP-0360246-A1 | 3-Oxiranyl benzoic acids and derivatives thereof | G.D. Searle & Co. (US) | 1990-03-28 | — | — | EP | disclosed |