Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MDH1 | P40925 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417247 | 1.00 | GRM2 (0.43) | GRM2TLR2FAAHEPHX2MDH1 | |
| SCHEMBL8415858 | 0.93 | GRM2 (0.41) | GRM2TLR2FAAHEPHX2MDH1 | |
| SCHEMBL8415854 | 0.93 | GRM2 (0.41) | GRM2TLR2FAAHEPHX2MDH1 | |
| SCHEMBL8416773 | 0.92 | GRM2 (0.41) | GRM2TLR2FAAHEPHX2MDH1 | |
| SCHEMBL8415832 | 0.92 | GRM2 (0.41) | GRM2TLR2FAAHEPHX2MDH1 | |
| SCHEMBL8416769 | 0.92 | GRM2 (0.41) | GRM2TLR2FAAHEPHX2MDH1 | |
| SCHEMBL8415851 | 0.92 | GRM2 (0.41) | GRM2TLR2FAAHEPHX2MDH1 | |
| SCHEMBL8415827 | 0.92 | GRM2 (0.41) | GRM2TLR2FAAHEPHX2MDH1 | |
| SCHEMBL8416771 | 0.88 | ALOX5 (0.48) | TLR2FAAHEPHX2 | |
| SCHEMBL8417334 | 0.87 | F7 (0.41) | TLR2EPHX2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2134375-A | — | — | None | — | — | JP | disclosed |
| US-5990326-A | AN ANTIINFLAMMATORY AGENT AS INHIBITORS OF LEUKOTRIENE HYDROLASE | G.D. SEARLE & CO. (US) | 1999-11-23 | — | — | US | disclosed |
| EP-0360246-B1 | 3-Oxiranyl benzoic acids and derivatives thereof | SEARLE & CO (US) | 1994-03-30 | — | — | EP | disclosed |
| JP-H02134375-A | 3-OXIRANYL BENZOATE AND ITS DERIVATIVE | G D SEARLE & CO | 1990-05-23 | — | — | JP | disclosed |
| EP-0360246-A1 | 3-Oxiranyl benzoic acids and derivatives thereof | G.D. Searle & Co. (US) | 1990-03-28 | — | — | EP | disclosed |