SCHEMBL841678

SCHEMBL841678

Nc1cccc2ncc3ccccc3c12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.57
GPR3 P46089 1/20 0.57
ALDH1A1 P00352 5/20 0.50
HPGD P15428 5/20 0.50
RAB9A P51151 4/20 0.50
LMNA P02545 3/20 0.50
GLA P06280 3/20 0.50
NPC1 O15118 2/20 0.50
POLB P06746 2/20 0.50
GAA P10253 2/20 0.50
KMT2A Q03164 2/20 0.50
PTBP1 P26599 1/20 0.50
RCE1 Q9Y256 1/20 0.50
HSD17B10 Q99714 4/20 0.47
CYP3A4 P08684 3/20 0.47
TSHR P16473 3/20 0.47
KEAP1 Q14145 1/20 0.47
MET P08581 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL856570 0.84 KDM4E (0.47) KDM4EGPR3ALDH1A1HPGDRAB9A
SCHEMBL27973182 0.83 GPR3 (0.64) KDM4EGPR3ALDH1A1HPGDRAB9A
SCHEMBL17239 0.82 KDM4E (0.43) KDM4EGPR3ALDH1A1HPGDRAB9A
SCHEMBL30857515 0.81 KDM4E (0.61) KDM4EGPR3ALDH1A1HPGDRAB9A
SCHEMBL17306541 0.80 KEAP1 (0.50) KDM4EGPR3ALDH1A1HPGDRAB9A
SCHEMBL10947562 0.80 KDM4E (0.50) KDM4EGPR3ALDH1A1HPGDRAB9A
SCHEMBL9038627 0.79 KDM4E (0.59) KDM4EGPR3ALDH1A1HPGDRAB9A
SCHEMBL10025808 0.78 GPR3 (0.68) KDM4EGPR3ALDH1A1HPGDRAB9A
SCHEMBL23003529 0.78 KDM4E (0.57) KDM4EGPR3ALDH1A1HPGDRAB9A
SCHEMBL460290 0.78 GPR3 (0.57) KDM4EGPR3ALDH1A1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119119404-A Covalent organic framework, preparation method thereof and application thereof in protein renaturation 南开大学 2024-12-13 CN claimed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN claimed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP claimed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN claimed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP claimed
CN-119119404-B Covalent organic framework, preparation method thereof and application thereof in protein renaturation 南开大学 2026-02-03 CN disclosed
CN-119119404-A Covalent organic framework, preparation method thereof and application thereof in protein renaturation 南开大学 2024-12-13 CN disclosed
CN-119119404-A Covalent organic framework, preparation method thereof and application thereof in protein renaturation 南开大学 2024-12-13 CN disclosed
EP-3996697-A1 NOVEL PFAR-INHIBITING COMPOUNDS Université de Bretagne Occidentale (U.B.O.) (FR) 2022-05-18 EP disclosed
WO-2021005189-A1 NOVEL PFAR-INHIBITING COMPOUNDS UNIVERSITE DE BRETAGNE OCCIDENTALE (UBO) (FR) 2021-01-14 WO disclosed
CN-109422685-A A kind of synthetic method of N- acetyl group phenanthridines -6- amide and its derivative 浙江工业大学 2019-03-05 CN disclosed
EP-2743274-B1 Organometallic complexes, organic electroluminescent device, and display using the same SAMSUNG ELECTRONICS CO LTD (KR) 2017-08-09 EP disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
CN-1204321-A Phenanthridine derivatives, process for preparing the same and drugs containing the same BERND CLEMENT (DE) 1999-01-06 CN disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed