Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417000 | 1.00 | TP53 (0.40) | TP53POLBGAACHRNB2CHRNA4 | |
| SCHEMBL379473 | 0.84 | MAPT (0.44) | GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL16420915 | 0.84 | GSK3B (0.40) | TP53POLBGAACHRNB2CHRNA4 | |
| SCHEMBL1722156 | 0.81 | GAA (0.44) | TP53POLBGAACHRNB2CHRNA4 | |
| SCHEMBL1722155 | 0.81 | GAA (0.44) | TP53POLBGAACHRNB2CHRNA4 | |
| SCHEMBL5067569 | 0.81 | POLB (0.39) | TP53POLBGAACHRNB2CHRNA4 | |
| SCHEMBL5067567 | 0.81 | POLB (0.39) | TP53POLBGAACHRNB2CHRNA4 | |
| SCHEMBL24221182 | 0.80 | GNAI3 (0.50) | — | |
| SCHEMBL23776245 | 0.80 | POLB (0.44) | TP53POLBGAACHRNB2CHRNA4 | |
| SCHEMBL19910363 | 0.78 | POLB (0.47) | POLBSMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |