Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005232 | 1.00 | CTSK (0.34) | CTSKNAAAPDE2ACYP2C9EPHX2 | |
| SCHEMBL8005238 | 1.00 | CTSK (0.34) | CTSKNAAAPDE2ACYP2C9EPHX2 | |
| SCHEMBL8005234 | 1.00 | CTSK (0.34) | CTSKNAAAPDE2ACYP2C9EPHX2 | |
| SCHEMBL8417308 | 0.92 | PDE2A (0.34) | PDE2ACYP2C9EPHX2ALDH1A1LMNA | |
| SCHEMBL8417305 | 0.92 | PDE2A (0.34) | PDE2ACYP2C9EPHX2ALDH1A1LMNA | |
| SCHEMBL9008525 | 0.91 | EPHX2 (0.32) | CTSKNAAAPDE2AEPHX2 | |
| SCHEMBL8015315 | 0.91 | EPHX2 (0.32) | CTSKNAAAPDE2AEPHX2 | |
| SCHEMBL8015320 | 0.91 | EPHX2 (0.32) | CTSKNAAAPDE2AEPHX2 | |
| SCHEMBL8015318 | 0.91 | EPHX2 (0.32) | CTSKNAAAPDE2AEPHX2 | |
| SCHEMBL9061975 | 0.88 | CTSK (0.38) | CTSKNAAAPDE2ACYP2C9EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5582764-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |