Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474769 | 0.82 | PSMB8 (0.64) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL721698 | 0.79 | PSMB8 (0.60) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL29392184 | 0.79 | PSMB8 (0.60) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL8229512 | 0.79 | PSMB8 (0.64) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL30903434 | 0.78 | PSMB8 (0.58) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL10474248 | 0.77 | PSMB8 (0.57) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL2754297 | 0.76 | PSMB8 (0.70) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL28259830 | 0.76 | PSMB8 (0.60) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL2711265 | 0.76 | PSMB8 (0.75) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL8417368 | 0.75 | PSMB8 (0.58) | PSMB8PSMB5CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638564-B1 | BENZOTHIAZOLESULFONAMIDE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | ASAHI CHEMICAL IND (JP) | 1999-09-01 | — | — | EP | disclosed |
| US-5504098-A | ANTIASTHMA AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0638564-A1 | BENZOTHIAZOLESULFONAMIDE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-02-15 | — | — | EP | disclosed |