Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.75 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.75 |
| ▸ | CA12 | O43570 | 1/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.72 |
| ▸ | CA2 | P00918 | 1/20 | 0.72 |
| ▸ | CA4 | P22748 | 1/20 | 0.72 |
| ▸ | CA7 | P43166 | 1/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.72 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651472 | 0.89 | PSMB8 (0.66) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL329577 | 0.86 | PSMB8 (0.72) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL29164335 | 0.86 | PSMB8 (1.00) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL30817868 | 0.86 | PSMB8 (1.00) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL11786164 | 0.85 | CA2 (0.68) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL23626381 | 0.84 | PSMB8 (0.70) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL329578 | 0.84 | PSMB8 (0.70) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL13851203 | 0.84 | PSMB8 (0.70) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL10336550 | 0.84 | PSMB8 (0.70) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL75415 | 0.84 | PSMB8 (0.70) | PSMB8PSMB5CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677768-A | Synthesis method of (3R) -tert-butyldimethylsilyloxy-5-oxo-6-triphenylphosphine alkene methyl hexanoate | 宿迁阿尔法科技有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-107698580-A | A kind of benzothiazole sulfone compound, its preparation method and application | 上海彩迩文生化科技有限公司 | 2018-02-16 | — | — | CN | claimed |
| US-9365561-B2 | C5 benzothiazolyl sulfone compound, method of preparing preparing the same, method of preparing polyene dialdehyde compound using the same, and method of synthesizing lycopene using the same | MYONGJI UNIVERSITY INDUSTRY AND ACADEMIA COOPERATION FOUNDATION (KR) | 2016-06-14 | — | — | US | claimed |
| US-20150376175-A1 | C5 BENZOTHIAZOLYL SULFONE COMPOUND, METHOD OF PREPARING THE SAME, METHOD OF PREPARING POLYENE DIALDEHYDE COMPOUND USING THE SAME, AND METHOD OF SYNTHESIZING LYCOPENE USING THE SAME | MYONGJI UNIVERSITY INDUSTRY AND ACADEMIA COOPERATION FOUNDATION (KR) | 2015-12-31 | — | — | US | claimed |
| WO-2010077062-A2 | PREPARATION METHOD OF STATIN COMPOUND AND BENZOTHIAZOLYL SULFONE COMPOUND USED THEREIN | HANMI PHARM. CO., LTD. (KR) | 2010-07-08 | — | — | WO | claimed |
| JP-1230566-A | — | — | None | — | — | JP | disclosed |
| EP-3237377-B1 | VITAMIN D3 DERIVATIVES AND PHARMACEUTICAL USE THEREOF | UNIV KYOTO (JP) | 2025-02-26 | — | — | EP | disclosed |
| CN-118005604-A | Synthesis and separation method of high-efficiency high-selectivity o-tolidine sulfone | 中国科学院山西煤炭化学研究所 | 2024-05-10 | — | — | CN | disclosed |
| US-20230407293-A1 | DNA-ENCODED AND AFFINITY-TAGGED MASKED-WARHEAD COMPOUNDS AND USE THEREOF IN ASSEMBLING LIBRARIES OF SMALL MOLECULES ENABLED FOR LATE-STAGE PURIFICATION AND MULTIPLEXED SCREENING OF COVALENT LIGANDS | MAIANTI JUAN PABLO (US) | 2023-12-21 | — | — | US | disclosed |
| US-20230278955-A1 | VITAMIN D3 DERIVATIVES AND PHARMACEUTICAL USE THEREOF | UNIV KYOTO (JP) | 2023-09-07 | — | — | US | disclosed |
| CN-116710467-A | Photooxidation reduction protein modification | 罗莎琳德·富兰克林研究所 | 2023-09-05 | — | — | CN | disclosed |
| US-20230272002-A1 | PHOTOREDOX PROTEIN MODIFICATION | THE ROSALIND FRANKLIN INSTITUTE (GB) | 2023-08-31 | — | — | US | disclosed |
| EP-1421389-A2 | NEUROFIBRILLARY LABELS | The University Court of The University of Aberdeen (GB) | 2004-05-26 | — | — | EP | disclosed |
| WO-2002075318-A3 | NEUROFIBRILLARY LABELS | UNIV ABERDEEN (GB) | 2004-03-11 | — | — | WO | disclosed |
| EP-0984927-B1 | DERIVATIVES OF 4,4-DIFLUOROBUT-3-ENYLSULFINIC ACID AND THEIR USE AS PESTICIDES | SYNGENTA LTD (GB) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002075318-A2 | NEUROFIBRILLARY LABELS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2002-09-26 | — | — | WO | disclosed |
| US-6274632-B1 | CONTROLLING AGRICULTURAL INSECTS | ZENECA LIMITED (GB) | 2001-08-14 | — | — | US | disclosed |
| EP-0984927-A1 | DERIVATIVES OF 4,4-DIFLUOROBUT-3-ENYLSULFINIC ACID AND THEIR USE AS PESTICIDES | ZENECA LIMITED (GB) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998040352-A1 | DERIVATIVES OF 4,4-DIFLUOROBUT-3-ENYLSULFINIC ACID AND THEIR USE AS PESTICIDES | ZENECA LIMITED (GB) | 1998-09-17 | — | — | WO | disclosed |
| JP-H01230566-A | STABILIZATION OF SULFENAMIDE-TYPE VULCANIZATION ACCELERATOR | SANSHIN KAGAKU KOGYO KK | 1989-09-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230407293-A1 | DNA-ENCODED AND AFFINITY-TAGGED MASKED-WARHEAD COMPOUNDS AND USE THEREOF IN ASSEMBLING LIBRARIES OF SMALL MOLECULES ENABLED FOR LATE-STAGE PURIFICATION AND MULTIPLEXED SCREENING OF COVALENT LIGANDS | DNA2, WRN, DCLRE1A | PSMB8 2953/4885PSMB5 3134/4885CA12 4337/4885 |
| US-20230272002-A1 | PHOTOREDOX PROTEIN MODIFICATION | PPOX, CACYBP, BRI3BP | PSMB8 1159/4885PSMB5 269/4885CA12 639/4885 |
| US-20230278955-A1 | VITAMIN D3 DERIVATIVES AND PHARMACEUTICAL USE THEREOF | VDR, CYP24A1, CYP2R1 | PSMB8 4750/4885PSMB5 4361/4885CA12 4220/4885 |
| US-20150376175-A1 | C5 BENZOTHIAZOLYL SULFONE COMPOUND, METHOD OF PREPARING THE SAME, METHOD OF PREPARING POLYENE DIALDEHYDE COMPOUND USING THE SAME, AND METHOD OF SYNTHESIZING LYCOPENE USING THE SAME | ALOX12, ALOX5, NOTUM | PSMB8 1277/4885PSMB5 431/4885CA12 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.