Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985918 | 0.84 | SMN1; SMN2 (0.58) | PSMB8PSMB5CA1CA2CA12 | |
| SCHEMBL8799536 | 0.81 | CA1 (0.70) | PSMB8PSMB5CA1CA2CA12 | |
| SCHEMBL10474769 | 0.81 | PSMB8 (0.64) | PSMB8PSMB5CA1CA2CA12 | |
| SCHEMBL8229512 | 0.81 | PSMB8 (0.64) | PSMB8PSMB5CA1CA2CA12 | |
| SCHEMBL31452859 | 0.80 | TARS1 (0.61) | PSMB8PSMB5CA1CA2CA12 | |
| SCHEMBL721698 | 0.78 | PSMB8 (0.60) | PSMB8PSMB5CA1CA2CA12 | |
| SCHEMBL29392184 | 0.78 | PSMB8 (0.60) | PSMB8PSMB5CA1CA2CA12 | |
| SCHEMBL8799206 | 0.78 | CA1 (0.54) | PSMB8PSMB5CA1CA2CA12 | |
| SCHEMBL8417366 | 0.77 | PSMB8 (0.58) | PSMB8PSMB5CA1CA2CA12 | |
| SCHEMBL30903434 | 0.77 | PSMB8 (0.58) | PSMB8PSMB5CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975449-A | EYE DROP FOR REDUCING INTRAOCULAR EYE PRESSURE | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1990-12-04 | — | — | US | disclosed |