Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9193429 | 0.84 | ALDH1A1 (0.48) | MAPTRAB9AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7008730 | 0.74 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL3976878 | 0.73 | ALDH1A1 (0.46) | MAPTKDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL30443207 | 0.73 | ALDH1A1 (0.46) | MAPTKDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL6064418 | 0.72 | GRIA2 (0.41) | MAPTKDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL30660078 | 0.72 | ALDH1A1 (0.48) | KDM4EALDH1A1HSD17B10TDP1L3MBTL1 | |
| SCHEMBL3982628 | 0.72 | ALDH1A1 (0.48) | KDM4EALDH1A1HSD17B10TDP1L3MBTL1 | |
| SCHEMBL9638043 | 0.71 | LTB4R2 (0.43) | MAPTKDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL8421301 | 0.71 | RAB9A (0.48) | MAPTRAB9AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8566925 | 0.70 | ESR2 (0.36) | MAPTALDH1A1TDP1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962491-A | ANGIOTENSIN ANTAGONIST, HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS, STROKES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5705517-A | ANGIOTENSIN II ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| US-5703110-A | HYPOTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| US-5328919-A | Antagonist of Angiotensin for cardiovascular disorders and hypotensive | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-07-12 | — | — | US | disclosed |