Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421350 | 0.97 | TBXAS1 (0.44) | TBXAS1TBXA2RNPSR1UTS2REEF2K | |
| SCHEMBL8419567 | 0.96 | TBXAS1 (0.45) | TBXAS1TBXA2RNPSR1UTS2REEF2K | |
| SCHEMBL8418155 | 0.94 | TBXAS1 (0.43) | TBXAS1TBXA2RNPSR1UTS2REEF2K | |
| SCHEMBL8418045 | 0.91 | LMNA (0.43) | TBXAS1TBXA2RNPSR1EEF2KALDH1A1 | |
| SCHEMBL8417483 | 0.90 | TBXAS1 (0.46) | TBXAS1TBXA2RNPSR1UTS2REEF2K | |
| SCHEMBL8419685 | 0.90 | UTS2R (0.42) | TBXAS1TBXA2RNPSR1UTS2REEF2K | |
| SCHEMBL8421496 | 0.89 | LMNA (0.42) | TBXAS1TBXA2RNPSR1EEF2KALDH1A1 | |
| SCHEMBL8417481 | 0.89 | TBXAS1 (0.46) | TBXAS1TBXA2RNPSR1UTS2REEF2K | |
| SCHEMBL8418087 | 0.89 | TBXAS1 (0.47) | TBXAS1TBXA2RNPSR1UTS2REEF2K | |
| SCHEMBL8421648 | 0.88 | TBXAS1 (0.47) | TBXAS1TBXA2RNPSR1UTS2REEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |