Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.56 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961092 | 0.86 | F10 (0.55) | FABP4FABP5KDM4EPLA2G10ALDH1A1 | |
| SCHEMBL699819 | 0.81 | GPR35 (0.53) | KDM4EPLA2G10ALDH1A1POLBSLC9A1 | |
| SCHEMBL7955701 | 0.78 | F10 (0.57) | FABP4FABP5KDM4EPLA2G10ALDH1A1 | |
| SCHEMBL2276306 | 0.76 | SLC9A1 (0.64) | KDM4EMCL1PLA2G10ALDH1A1SLC9A1 | |
| SCHEMBL7947022 | 0.76 | F10 (0.55) | KDM4EALDH1A1HSD17B10CYP1A2F10 | |
| SCHEMBL28815311 | 0.74 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8260 | 0.73 | DAO (0.59) | FABP4KDM4EMCL1PLA2G10ALDH1A1 | |
| SCHEMBL27343262 | 0.73 | KDM4E (0.54) | FABP4FABP5KDM4EPLA2G10ALDH1A1 | |
| SCHEMBL8691540 | 0.73 | BACE1 (0.43) | KDM4EALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL3277134 | 0.73 | F10 (0.57) | KDM4EMCL1CMA1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977100-A | Substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5834454-A | TREATMENT OF ANGINA, ISCHEMIA, ARRHYTHMIA | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-11-10 | — | — | US | disclosed |