Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 4/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418190 | 0.84 | CYP19A1 (0.58) | CYP19A1ALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8415790 | 0.81 | HTR2C (0.67) | CYP19A1ALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9053943 | 0.80 | HTR6 (0.47) | CYP19A1ALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9056948 | 0.80 | POLB (0.53) | CYP19A1ALDH1A1RXFP1MEN1KMT2A | |
| SCHEMBL8418107 | 0.78 | CYP19A1 (0.56) | CYP19A1ALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9056449 | 0.77 | CYP19A1 (0.55) | CYP19A1ALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8416389 | 0.75 | HTR2C (0.59) | CYP19A1KMT2APOLBHTR6HTR2C | |
| SCHEMBL8415599 | 0.75 | HTR2C (0.65) | CYP19A1ALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9055307 | 0.75 | YES1 (0.69) | CYP19A1POLBHTR6HTR2CHDAC10 | |
| Fumaric Acid SCHEMBL8416954 | 0.74 | HTR2C (0.60) | CYP19A1ALDH1A1CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965582-A | ANTIHISTAMINES | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1999-10-12 | — | — | US | claimed |