Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023787 | 1.00 | LMNA (0.45) | LMNAKCNH2MEN1NPC1CACNA1F | |
| SCHEMBL8418142 | 1.00 | LMNA (0.45) | LMNAKCNH2MEN1NPC1CACNA1F | |
| SCHEMBL6055419 | 0.83 | LMNA (0.46) | LMNAKCNH2MEN1NPC1CACNA1F | |
| SCHEMBL6827541 | 0.83 | LMNA (0.46) | LMNAKCNH2MEN1NPC1CACNA1F | |
| SCHEMBL2453332 | 0.82 | LMNA (0.51) | LMNAKCNH2MEN1NPC1CACNA1F | |
| SCHEMBL9234803 | 0.82 | RIPK1 (0.37) | LMNAKCNH2MEN1NPC1CACNA1F | |
| SCHEMBL9235767 | 0.82 | RIPK1 (0.37) | LMNAKCNH2MEN1NPC1CACNA1F | |
| SCHEMBL9235978 | 0.82 | RIPK1 (0.37) | LMNAKCNH2MEN1NPC1CACNA1F | |
| SCHEMBL24298369 | 0.81 | LMNA (0.45) | LMNAKCNH2MEN1NPC1CACNA1F | |
| SCHEMBL3187891 | 0.81 | LMNA (0.45) | LMNAKCNH2MEN1NPC1CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118620972-A | Application of halohydrin dehalogenase in catalytic synthesis of chiral tetrahydrofuran compound | 南京工业大学 | 2024-09-10 | — | — | CN | claimed |
| CN-118222538-B | Halohydrin dehalogenase mutant and application thereof | 南京工业大学 | 2024-09-20 | — | — | CN | disclosed |
| CN-118620972-A | Application of halohydrin dehalogenase in catalytic synthesis of chiral tetrahydrofuran compound | 南京工业大学 | 2024-09-10 | — | — | CN | disclosed |
| CN-118222538-A | Halohydrin dehalogenase mutant and application thereof | 南京工业大学 | 2024-06-21 | — | — | CN | disclosed |
| EP-0713848-B1 | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS COMPANY (JP) | 1999-09-08 | — | — | EP | disclosed |
| EP-0292735-B1 | PROCESS FOR PREPARING ALPHA-(ALKYLPHENYL)-4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINE BUTANOL | ERREGIERRE INDUSTRIA CHIMICA Spa (IT) | 1992-08-19 | — | — | EP | disclosed |
| US-5112978-A | Preparation of terfenadine | ERREGIERRE INDUSTRIA CHIMICA S.P.A. (IT) | 1992-05-12 | — | — | US | disclosed |
| EP-0292735-A1 | Process for preparing alpha-(alkylphenyl)-4-(hydroxydiphenylmethyl)-1-piperidine butanol | ERREGIERRE INDUSTRIA CHIMICA Spa (IT) | 1988-11-30 | — | — | EP | disclosed |