Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EEF2K | O00418 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CCR9 | P51686 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419380 | 0.99 | UTS2R (0.42) | UTS2RTBXAS1TBXA2RMEN1KMT2A | |
| SCHEMBL8421571 | 0.94 | UTS2R (0.42) | UTS2RTBXAS1TBXA2RMEN1KMT2A | |
| SCHEMBL8417486 | 0.93 | UTS2R (0.43) | UTS2RTBXAS1TBXA2RMEN1KMT2A | |
| SCHEMBL8894772 | 0.92 | UTS2R (0.44) | UTS2RTBXAS1TBXA2RMEN1KMT2A | |
| SCHEMBL8419454 | 0.92 | UTS2R (0.44) | UTS2RTBXAS1TBXA2RMEN1KMT2A | |
| SCHEMBL8419365 | 0.92 | SIGMAR1 (0.40) | EEF2KALDH1A1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL8421534 | 0.91 | SIGMAR1 (0.39) | EEF2KALDH1A1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL8417479 | 0.90 | UTS2R (0.42) | UTS2RTBXAS1TBXA2RMEN1KMT2A | |
| SCHEMBL8896048 | 0.90 | UTS2R (0.45) | UTS2RTBXAS1TBXA2RMEN1KMT2A | |
| SCHEMBL8417515 | 0.90 | TBXAS1 (0.47) | UTS2RTBXAS1TBXA2REEF2KNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |