Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363620 | 0.88 | L3MBTL1 (0.62) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL7601476 | 0.86 | L3MBTL1 (0.61) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL12267104 | 0.84 | L3MBTL1 (0.67) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL14561488 | 0.83 | L3MBTL1 (0.57) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL8226165 | 0.83 | L3MBTL1 (0.57) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL14363616 | 0.83 | L3MBTL1 (0.57) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL12021892 | 0.83 | L3MBTL1 (0.57) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL8282433 | 0.83 | L3MBTL1 (0.57) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL27364860 | 0.83 | L3MBTL1 (0.57) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL19294277 | 0.81 | L3MBTL1 (0.54) | L3MBTL1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191445-B1 | CYCLOBUTANE CONTAINING CARBOXYLIC ACID GPR120 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2019-06-12 | — | — | EP | disclosed |
| US-7968156-B2 | Compound, composition, retardation plate, elliptically-polarizing plate and liquid-crystal display device | FUJIFILM CORPORATION (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7968157-B2 | Discotic nematic material, composition, retardation plate, elliptically-polarizing plate and compound | FUJIFILM CORPORATION (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7944530-B2 | Optical film, polarizing plate and liquid crystal display device including an optically anisotropic layer formed from a mixture including two or more liquid crystal compounds | FUJIFILM CORPORATION (JP) | 2011-05-17 | — | — | US | disclosed |
| US-20090233009-A1 | COMPOUND, COMPOSITION, RETARDATION PLATE, ELLIPTICALLY-POLARIZING PLATE AND LIQUID-CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| US-20090068378-A1 | DISCOTIC NEMATIC MATERIAL, COMPOSITION, RETARDATION PLATE, ELLIPTICALLY-POLARIZING PLATE AND COMPOUND | FUJIFILM CORPORATION (JP) | 2009-03-12 | — | — | US | disclosed |
| US-7465740-B2 | 2-heteroaryl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists | SCHERING CORPORATION (US) | 2008-12-16 | — | — | US | disclosed |
| US-7431972-B2 | Optical film, and polarizing plate and liquid crystal display device using the same | FUJIFILM CORPORATION (JP) | 2008-10-07 | — | — | US | disclosed |
| US-20070065601-A1 | Optical film, and polarizing plate and liquid crystal display device using the same | FUJI PHOTO FILM CO., LTD. (JP) | 2007-03-22 | — | — | US | disclosed |
| US-20070066620-A1 | 2-Heteroaryl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists | MERCK SHARP & DOHME LLC | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066620-A1 | 2-Heteroaryl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists | ADORA2A, ADORA3, ADORA1 | L3MBTL1 4142/4885CA12 4809/4885CA1 3419/4885 |
| US-20090068378-A1 | DISCOTIC NEMATIC MATERIAL, COMPOSITION, RETARDATION PLATE, ELLIPTICALLY-POLARIZING PLATE AND COMPOUND | H1-2, H1-0, CCNL2 | L3MBTL1 927/4885CA12 3622/4885CA1 3693/4885 |
| US-20090233009-A1 | COMPOUND, COMPOSITION, RETARDATION PLATE, ELLIPTICALLY-POLARIZING PLATE AND LIQUID-CRYSTAL DISPLAY DEVICE | PYM1, CCNA1, CCND1 | L3MBTL1 607/4885CA12 787/4885CA1 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.