SCHEMBL84185

SCHEMBL84185

c1ccc(C2=NCCO2)cc1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.47
KCNH2 Q12809 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
LTA4H P09960 1/20 0.41
MMP12 P39900 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
LMNA P02545 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
USP9X Q93008 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21351777 1.00 KCNN4 (0.47) KCNN4KCNH2HRH3SMN1; SMN2ADRA2A
SCHEMBL9566190 0.98 KCNN4 (0.46) KCNN4KCNH2HRH3SMN1; SMN2ADRA2A
SCHEMBL961792 0.96 KCNN4 (0.44) KCNN4KCNH2HRH3SMN1; SMN2ADRA2A
SCHEMBL28451854 0.94 KCNN4 (0.43) KCNN4KCNH2HRH3SMN1; SMN2ADRA2A
SCHEMBL2681836 0.89 KCNN4 (0.40) KCNN4KCNH2HRH3SMN1; SMN2ADRA2A
Perchlorate SCHEMBL9083550 0.89 LMNA (0.40) KCNN4KCNH2HRH3SMN1; SMN2ADRA2A
SCHEMBL132013 0.88 KCNH2 (0.49) KCNN4KCNH2HRH3SMN1; SMN2LTA4H
SCHEMBL9319771 0.87 CHRNB4 (0.44) KCNN4KCNH2HRH3SMN1; SMN2ADRA2A
SCHEMBL27260114 0.86 NISCH (0.46) KCNN4SMN1; SMN2ADRA2AADRA2BADRA2C
SCHEMBL27783589 0.86 SMN1; SMN2 (0.38) KCNN4KCNH2HRH3SMN1; SMN2ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2171 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079979-A Benzofuran derivative and medical application thereof 2026-05-26 CN claimed
CN-122095296-A Dimming sheet, dimming device and manufacturing method of dimming sheet 2026-05-26 CN claimed
EP-4185571-B1 SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS UNIV OF KWAZULU NATAL (ZA) 2026-05-20 EP claimed
US-20260117393-A1 ETCHING AGENT COMPOSITION AND ETCHING METHOD USING THE SAME KCTECH CO., LTD. (KR) 2026-04-30 US claimed
EP-4656669-A1 FLUORINATED COPOLYMERS BASED ON AN OLIGO(2-OXAZOLINE) MACROMONOMER ARKEMA FRANCE (FR) 2025-12-03 EP claimed
US-12441721-B2 Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols UNIVERSITY OF KWAZULU-NATAL (ZA) 2025-10-14 US claimed
US-20250176536-A1 ANTIMICROBIAL AND/OR ANTIVIRAL MATERIALS KLURA LTD (GB) 2025-06-05 US claimed
CN-120082046-A Synthesis method of polysulfone family-b-polyoxazoline block copolymer 天津工业大学 2025-06-03 CN claimed
CN-120059201-A Synthesis method of polysulfone block copolymer 沧州市天津工业大学研究院 2025-05-30 CN claimed
CN-115380054-B Amine modified polymers, controlled radical polymerization for their preparation and their implementation 巴斯夫欧洲公司 2025-05-13 CN claimed
WO-1993005871-A1 HYDROPHILIC MEMBRANES PREPARED FROM POLYETHERSULFONE/POLY-2-OXAZOLINE/POLYVINYLPYRROLIDONE BLEND GELMAN SCIENCES INC. (US) 1993-04-01 WO claimed
US-5178765-A High strength GELMAN SCIENCES INC. (US) 1993-01-12 US claimed
EP-0501409-A2 Liquid crystal display device and preparation thereof SUMITOMO ELECTRIC INDUSTRIES, LTD (JP) 1992-09-02 EP claimed
EP-0266708-B1 CROSS-LINKED RESINS AND PRODUCTION THEREOF TAKEDA CHEMICAL INDUSTRIES, Ltd. (JP) 1991-07-03 EP claimed
EP-0432661-A2 2-Substituted phenyl-2-oxazoline or thiazoline derivatives, process for producing the same and insecticides and acaricides containing the same YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) 1991-06-19 EP claimed
US-5017644-A Ink jet ink compositions XEROX CORPORATION (US) 1991-05-21 US claimed
US-4839446-A LOW VISCOSITY AT MODERATE TEMPERATURE ASHLAND OIL, INC. (US) 1989-06-13 US claimed
US-4837302-A STRENGTH AND HEAT RESISTANCE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-06-06 US claimed
EP-0266708-A1 Cross-linked resins and production thereof TAKEDA CHEMICAL INDUSTRIES, Ltd. (JP) 1988-05-11 EP claimed
US-4016192-A Unsaturated acrylic acid-oxazoline reaction products THE DOW CHEMICAL COMPANY (US) 1977-04-05 US claimed