Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.77 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.58 |
| ▸ | TUBB | P07437 | 3/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16894627 | 0.88 | ADORA3 (0.64) | ABCB1ABCG2KDM4EMAPTGAA | |
| 3,5,6,7,8,3',4'-Heptamethoxyflavone SCHEMBL31621487 | 0.87 | ABCG2 (1.00) | ABCB1ABCG2KDM4EMAPTGAA | |
| 3,5,6,7,8,3',4'-Heptamethoxyflavone SCHEMBL1764676 | 0.87 | ABCG2 (1.00) | ABCB1ABCG2KDM4EMAPTGAA | |
| 3,5,6,7,8,3',4'-Heptamethoxyflavone SCHEMBL29467229 | 0.87 | ABCG2 (1.00) | ABCB1ABCG2KDM4EMAPTGAA | |
| SCHEMBL23092913 | 0.84 | ABCG2 (0.79) | ABCB1ABCG2KDM4EMAPTGAA | |
| SCHEMBL31287150 | 0.82 | ADORA3 (0.72) | ABCB1ABCG2KDM4EMAPTADORA3 | |
| SCHEMBL16894654 | 0.82 | ADORA3 (0.72) | ABCB1ABCG2KDM4EMAPTADORA3 | |
| SCHEMBL27193010 | 0.81 | TUBB4A (0.86) | ABCB1ABCG2KDM4EMAPTGAA | |
| SCHEMBL30082746 | 0.81 | TUBB4A (0.86) | ABCB1ABCG2KDM4EMAPTGAA | |
| SCHEMBL16549448 | 0.80 | BCL9 (0.57) | ABCB1ABCG2KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669003-B2 | Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs | JIN YONGRI (CN) | 2017-06-06 | — | — | US | claimed |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | JIN YONGRI (CN) | 2015-07-16 | — | — | US | claimed |
| EP-0605261-B1 | Use of a flavone derivative as taste modifier and a method of modifying taste | SAN EI GEN FFI INC (JP) | 1999-09-15 | — | — | EP | claimed |
| US-5580545-A | ADDING FLAVONE DERIVATIVES TO FOODS, BEVERAGES OR TOILETRIES TO ENHANCE OR REDUCE FLAVORS | SAN-EI GEN F.F.I., INC. (JP) | 1996-12-03 | — | — | US | claimed |
| EP-0605261-A2 | A taste modifier and a method of modifying taste | SAN-EI GEN F.F.I., INC. (JP) | 1994-07-06 | — | — | EP | claimed |
| CN-107889461-B | Immunoactive botanical blends and their use in methods for preventing and treating rashes | 雷娜特·维尔马诺维兹 | 2022-03-08 | — | — | CN | disclosed |
| CN-110664798-A | Mu opioid receptor agonist and application thereof | 南京中医药大学 | 2020-01-10 | — | — | CN | disclosed |
| US-9669003-B2 | Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs | JIN YONGRI (CN) | 2017-06-06 | — | — | US | disclosed |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | JIN YONGRI (CN) | 2015-07-16 | — | — | US | disclosed |
| CN-101257911-A | Methods for managing adipocyte fat accumulation | WELLGEN INC (US) | 2008-09-03 | — | — | CN | disclosed |
| EP-0605261-B1 | Use of a flavone derivative as taste modifier and a method of modifying taste | SAN EI GEN FFI INC (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-5580545-A | ADDING FLAVONE DERIVATIVES TO FOODS, BEVERAGES OR TOILETRIES TO ENHANCE OR REDUCE FLAVORS | SAN-EI GEN F.F.I., INC. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0605261-A2 | A taste modifier and a method of modifying taste | SAN-EI GEN F.F.I., INC. (JP) | 1994-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | CYP2D6, GATAD2A, CYP3A43 | ABCB1 218/4885ABCG2 98/4885KDM4E 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.