Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | HTT | P42858 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395368 | 0.94 | ALDH1A1 (0.66) | MAPTALDH1A1KMT2AHTTKDM4E | |
| SCHEMBL11316773 | 0.91 | ALDH1A1 (0.55) | MAPTALDH1A1KMT2AHTTKDM4E | |
| SCHEMBL10654204 | 0.87 | ALDH1A1 (0.60) | MAPTALDH1A1KMT2AHTTKDM4E | |
| Methyl Alcohol SCHEMBL1028813 | 0.85 | MAPT (0.69) | MAPTALDH1A1KMT2AHTTKDM4E | |
| SCHEMBL34121 | 0.84 | ALDH1A1 (0.68) | MAPTALDH1A1KMT2AHTTKDM4E | |
| SCHEMBL9150171 | 0.84 | ALDH1A1 (0.68) | MAPTALDH1A1KMT2AHTTKDM4E | |
| SCHEMBL5425653 | 0.84 | ALDH1A1 (0.68) | MAPTALDH1A1KMT2AHTTKDM4E | |
| SCHEMBL393039 | 0.84 | ALDH1A1 (0.53) | MAPTALDH1A1KMT2AHTTKDM4E | |
| SCHEMBL10698670 | 0.84 | ALDH1A1 (0.53) | MAPTALDH1A1KMT2AHTTKDM4E | |
| SCHEMBL10607053 | 0.82 | ALDH1A1 (0.54) | MAPTALDH1A1KMT2AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804510-B1 | MONOAZO PIGMENTS | ZENECA LTD (GB) | 1999-09-08 | — | — | EP | claimed |
| US-5037449-A | For dyeing or printing cotton or wool | CIBA-GEIGY CORPORATION (US) | 1991-08-06 | — | — | US | disclosed |