SCHEMBL393039

SCHEMBL393039

Cc1cc(=O)n(-c2cccc(S(=O)(=O)O)c2)[nH]1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.53
MAPT P10636 6/20 0.53
KDM4E B2RXH2 4/20 0.53
KMT2A Q03164 4/20 0.53
GAA P10253 2/20 0.53
HTT P42858 2/20 0.53
MEN1 O00255 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
LMNA P02545 2/20 0.47
RECQL P46063 1/20 0.47
ALKBH5 Q6P6C2 5/20 0.46
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ALKBH3 Q96Q83 1/20 0.39
KDM5A P29375 1/20 0.38
KDM2B Q8NHM5 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
POLB P06746 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10698670 1.00 ALDH1A1 (0.53) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL11316773 0.95 ALDH1A1 (0.55) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL9789614 0.85 CA1 (0.49) ALDH1A1MAPTKDM4EKMT2AGAA
Anthranilic Acid SCHEMBL11706693 0.85 ALDH1A1 (0.45) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL10607599 0.84 MAPT (0.54) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL8040128 0.84 ALDH1A1 (0.39) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL8418696 0.84 MAPT (0.59) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL11697702 0.83 MAPT (0.41) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL395368 0.83 ALDH1A1 (0.66) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL10607053 0.83 ALDH1A1 (0.54) ALDH1A1MAPTKDM4EKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2421613-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF The Procter & Gamble Company (US) 2012-02-29 EP claimed
EP-2125965-B1 PIGMENT COMPOSITION BASED ON C.I. PIGMENT YELLOW 191 CLARIANT FINANCE BVI LTD (VG) 2011-11-23 EP claimed
US-7985266-B2 Keratin dyeing compositions comprising a radical scavenger and a chelant and use thereof THE PROCTER & GAMBLE COMPANY (US) 2011-07-26 US claimed
US-20110035886-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof NOXELL CORPORATION 2011-02-17 US claimed
US-7824488-B2 Pigment composition based on C.I. pigment yellow 191 CLARIANT FINANCE (BVI) LIMITED (VG) 2010-11-02 US claimed
WO-2010123866-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2010-10-28 WO claimed
US-20100099039-A1 Pigment Composition Based on C.I. Pigment Yellow 191 CLARIANT INTERNATIONAL LTD. (CH) 2010-04-22 US claimed
EP-2125965-A1 PIGMENT COMPOSITION BASED ON C.I. PIGMENT YELLOW 191 Clariant Finance (BVI) Limited (VG) 2009-12-02 EP claimed
WO-2008101612-A1 PIGMENT COMPOSITION BASED ON C.I. PIGMENT YELLOW 191 CLARIANT FINANCE (BVI) LIMITED (VG) 2008-08-28 WO claimed
EP-1343847-B1 TRANSPARENT GREENISH YELLOW PYRAZOLONE PIGMENTS BASF AG (DE) 2005-05-18 EP claimed
US-5744590-A Monoazo pigments ZENECA LIMITED (GB) 1998-04-28 US claimed
EP-0804510-A1 MONOAZO PIGMENTS ZENECA LIMITED (GB) 1997-11-05 EP claimed
EP-0804509-A1 MONOAZO PIGMENTS ZENECA LIMITED (GB) 1997-11-05 EP claimed
WO-1996022333-A1 MONOAZO PIGMENTS ZENECA LIMITED (GB) 1996-07-25 WO claimed
WO-1996022334-A1 MONOAZO PIGMENTS ZENECA LIMITED (GB) 1996-07-25 WO claimed
EP-0263951-B1 Disazo compounds and compositions containing them BASF LACKE & FARBEN (DE) 1994-06-15 EP claimed
US-4894094-A HEAT RESISTANT PRINTING INKS BASF LACKE & FARBEN AKTIENGESELLSCHAFT (DE) 1990-01-16 US claimed
EP-0263951-A2 Disazo compounds and compositions containing them BASF Lacke + Farben AG (DE) 1988-04-20 EP claimed
EP-0062183-B1 RESIST PRINTING PROCESS BAYER AG (DE) 1986-07-02 EP claimed
US-4474695-A Complex dye mixture containing at least two cobalt 1:2 complexes of azo dyes BASF AKTIENGESELLSCHAFT (DE) 1984-10-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110035886-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof KRT18, LPO, KRTCAP2 ALDH1A1 354/4885MAPT 547/4885KDM4E 509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.