Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.50 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5300903 | 0.93 | HPGD (0.58) | HPGDPOLBALDH1A1MAPTGSTP1 | |
| SCHEMBL14476018 | 0.85 | HPGD (0.67) | HPGDPOLBALDH1A1MAPTVCAM1 | |
| SCHEMBL8102330 | 0.85 | HPGD (0.60) | HPGDPOLBALDH1A1MAPTVCAM1 | |
| SCHEMBL1995617 | 0.84 | HPGD (0.59) | HPGDPOLBALDH1A1MAPTVCAM1 | |
| SCHEMBL22226687 | 0.83 | GSTP1 (0.58) | HPGDPOLBALDH1A1MAPTGSTP1 | |
| SCHEMBL23768982 | 0.82 | HPGD (0.63) | HPGDPOLBALDH1A1MAPTVCAM1 | |
| SCHEMBL21291391 | 0.81 | HPGD (0.61) | HPGDPOLBALDH1A1MAPTVCAM1 | |
| SCHEMBL8420669 | 0.80 | KDM4E (0.57) | HPGDALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5917877 | 0.79 | HPGD (0.66) | HPGDPOLBALDH1A1MAPTVCAM1 | |
| SCHEMBL8892679 | 0.79 | HPGD (0.62) | HPGDPOLBALDH1A1MAPTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |