Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1995617 | 0.88 | HPGD (0.59) | HPGDPOLBALDH1A1MAPTVCAM1 | |
| SCHEMBL5300903 | 0.87 | HPGD (0.58) | HPGDPOLBALDH1A1MAPTVCAM1 | |
| SCHEMBL23768982 | 0.86 | HPGD (0.63) | HPGDPOLBALDH1A1MAPTVCAM1 | |
| SCHEMBL21291391 | 0.85 | HPGD (0.61) | HPGDPOLBALDH1A1MAPTVCAM1 | |
| SCHEMBL8418979 | 0.85 | HPGD (0.56) | HPGDPOLBALDH1A1MAPTCA2 | |
| SCHEMBL8427051 | 0.85 | CA2 (0.62) | ALDH1A1MAPTCA2VCAM1APEX1 | |
| SCHEMBL14476018 | 0.84 | HPGD (0.67) | HPGDPOLBALDH1A1MAPTVCAM1 | |
| SCHEMBL2001981 | 0.83 | APEX1 (0.72) | ALDH1A1MAPTCA2APEX1TDP1 | |
| SCHEMBL5917877 | 0.83 | HPGD (0.66) | HPGDPOLBALDH1A1MAPTVCAM1 | |
| SCHEMBL7357430 | 0.82 | HPGD (0.64) | HPGDPOLBALDH1A1MAPTVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031572-A1 | PYRIDYLPYRROLE DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-30 | — | — | EP | disclosed |