Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962500 | 0.91 | ALDH1A1 (0.50) | HTTEGFRERBB2KMT2AKDM4E | |
| SCHEMBL8418603 | 0.91 | HTT (0.50) | HTTEGFRERBB2KMT2AKDM4E | |
| SCHEMBL5013530 | 0.83 | ALDH1A1 (0.55) | HTTKDM4ENR1H4ALDH1A1SMN1; SMN2 | |
| SCHEMBL25660538 | 0.83 | KMT2A (0.61) | HTTKMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL13002831 | 0.82 | ALDH1A1 (0.61) | HTTKMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL12938525 | 0.79 | HSD17B1 (0.57) | HTTEGFRERBB2KMT2AKDM4E | |
| SCHEMBL6802143 | 0.79 | HSP90AA1 (0.60) | HTTEGFRERBB2KMT2AKDM4E | |
| SCHEMBL9094961 | 0.79 | KMT2A (0.56) | HTTEGFRERBB2KMT2AKDM4E | |
| SCHEMBL9096918 | 0.78 | NOTUM (0.65) | HTTKMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL24627774 | 0.78 | MAPT (0.73) | HTTKMT2AKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573573-B1 | MESOGENIC GLYCIDYL AMINES | DOW CHEMICAL CO (US) | 1999-09-29 | — | — | EP | claimed |
| EP-0573573-A1 | MESOGENIC GLYCIDYL AMINES | THE DOW CHEMICAL COMPANY (US) | 1993-12-15 | — | — | EP | claimed |
| WO-1992015630-A2 | MESOGENIC GLYCIDYL AMINES | THE DOW CHEMICAL COMPANY (US) | 1992-09-17 | — | — | WO | claimed |
| US-5360884-A | Coatings, adhesives, moldings, laminates and encapsulation | THE DOW CHEMICAL COMPANY (US) | 1994-11-01 | — | — | US | disclosed |
| US-5262509-A | Curable coatings | THE DOW CHEMICAL COMPANY (US) | 1993-11-16 | — | — | US | disclosed |