SCHEMBL8419009

SCHEMBL8419009

Oc1ccc(O)c(Sc2cc(O)ccc2O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 8/20 0.58
ALDH1A1 P00352 7/20 0.58
ALOX15 P16050 6/20 0.58
HPGD P15428 5/20 0.58
LMNA P02545 5/20 0.58
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
MAPT P10636 4/20 0.58
CYP3A4 P08684 4/20 0.58
HTT P42858 3/20 0.58
HIF1A Q16665 3/20 0.58
TP53 P04637 2/20 0.58
ALOX12 P18054 2/20 0.58
CYP2C9 P11712 2/20 0.58
GAA P10253 1/20 0.58
PLA2G1B P04054 1/20 0.58
HSP90AA1 P07900 1/20 0.58
CYP2D6 P10635 1/20 0.58
CYP2C19 P33261 1/20 0.58
ATG4B Q9Y4P1 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11728749 0.91 ALDH1A1 (0.50) HSD17B10ALDH1A1ALOX15HPGDLMNA
SCHEMBL11728615 0.83 HSD17B10 (0.42) HSD17B10ALDH1A1ALOX15HPGDLMNA
SCHEMBL2861898 0.82 HPGD (0.44) HSD17B10ALDH1A1ALOX15HPGDLMNA
SCHEMBL30912339 0.82 HPGD (0.52) HSD17B10ALDH1A1ALOX15HPGDLMNA
SCHEMBL2865432 0.82 HPGD (0.52) HSD17B10ALDH1A1ALOX15HPGDLMNA
SCHEMBL30912337 0.82 HPGD (0.52) HSD17B10ALDH1A1ALOX15HPGDLMNA
SCHEMBL30912340 0.82 HPGD (0.52) HSD17B10ALDH1A1ALOX15HPGDLMNA
SCHEMBL30912338 0.82 HPGD (0.52) HSD17B10ALDH1A1ALOX15HPGDLMNA
SCHEMBL24861268 0.81 HSD17B10 (0.39) HSD17B10ALDH1A1ALOX15HPGDLMNA
SCHEMBL17498348 0.80 ALOX15 (0.41) HSD17B10ALDH1A1ALOX15HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573573-B1 MESOGENIC GLYCIDYL AMINES DOW CHEMICAL CO (US) 1999-09-29 EP claimed
EP-0573573-A1 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1993-12-15 EP claimed
US-5266660-A Curable compositions containing mesogenic epoxy compounds and cured products thereof THE DOW CHEMICAL CO. (US) 1993-11-30 US claimed
US-5227452-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1993-07-13 US claimed
WO-1992015630-A2 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1992-09-17 WO claimed
EP-0475238-A2 Mesogenic glycidyl esters THE DOW CHEMICAL COMPANY (US) 1992-03-18 EP claimed
US-4518977-A Heat-sensitive recording sheet JUJO PAPER CO., LTD. (JP) 1985-05-21 US claimed
EP-0251741-B1 POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-08-21 EP disclosed
US-4737546-A IMPROVING MELT FLOW BY ADDING ETHYLENE-VINYL ACETATE COPOLYMER, RETAINED IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1988-04-12 US disclosed
US-4299946-A THERMOSETTING RESINS RHONE-POULENC INDUSTRIES (FR) 1981-11-10 US disclosed
US-4287366-A BY OXIDATION OF THE CORRESPONDING SULFIDE OR SULFOXIDE WITH HYDROGEN PEROXIDE IN THE PRESENCE OF AN ALKALI METAL HYDROXIDE MITSUI TOATSU CHEMICALS, INC. (JP) 1981-09-01 US disclosed
US-4275240-A OXIDATION OF 2,2'-BISPHENOL SULFIDES IN A SOLVENT MITSUI TOATSU CHEMICALS, INC. (JP) 1981-06-23 US disclosed
US-4120931-A ROLLING AND STRETCHING SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-10-17 US disclosed
US-4051078-A CURING DAINICHI-NIPPON CABLES, LTD. (JA) 1977-09-27 US disclosed