Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.39 |
| ▸ | GLRB | P48167 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39475 | 1.00 | GPR84 (0.40) | GPR84LMNARECQLFFAR1NR5A2 | |
| SCHEMBL2542322 | 1.00 | GPR84 (0.40) | GPR84LMNARECQLFFAR1NR5A2 | |
| SCHEMBL11739834 | 1.00 | GPR84 (0.40) | GPR84LMNARECQLFFAR1NR5A2 | |
| SCHEMBL11728968 | 1.00 | GPR84 (0.40) | GPR84LMNARECQLFFAR1NR5A2 | |
| SCHEMBL11644932 | 0.90 | PPARG (0.40) | MAPTF2RKCNH2BLMGAA | |
| SCHEMBL6659436 | 0.89 | LMNA (0.40) | LMNARECQLFFAR1NR5A2NR5A1 | |
| SCHEMBL1278397 | 0.88 | LMNA (0.44) | LMNARECQLMAPTGLRA3GLRB | |
| SCHEMBL11614489 | 0.87 | LMNA (0.39) | LMNARECQLNR5A2NR5A1F2R | |
| SCHEMBL206895 | 0.87 | GMNN (0.37) | LMNARECQLNR5A2NR5A1MAPT | |
| SCHEMBL206012 | 0.87 | GMNN (0.37) | LMNARECQLNR5A2NR5A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990173-A | ANTICHOLESTEROL AGENTS; TREATING ATHEROSCLEROSIS; ENZYME INHIBITORS OF ACYLCOENZYME A:CHOLESTEROL ACYLTRANSFERASE (ACAT) | PIERRE FABRE MEDICAMENT (FR) | 1999-11-23 | — | — | US | disclosed |