Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896383 | 0.98 | NPSR1 (0.51) | NPSR1TBXAS1TBXA2RUTS2RALDH1A1 | |
| SCHEMBL8898428 | 0.97 | NPSR1 (0.50) | NPSR1TBXAS1TBXA2RUTS2RALDH1A1 | |
| SCHEMBL8894801 | 0.95 | NPSR1 (0.52) | NPSR1TBXAS1TBXA2RUTS2RALDH1A1 | |
| SCHEMBL8897696 | 0.92 | NPSR1 (0.51) | NPSR1TBXAS1TBXA2RUTS2RALDH1A1 | |
| SCHEMBL8894907 | 0.91 | NPSR1 (0.49) | NPSR1TBXAS1TBXA2RUTS2RALDH1A1 | |
| SCHEMBL8895766 | 0.90 | NPSR1 (0.51) | NPSR1TBXA2RALDH1A1ATML3MBTL1 | |
| SCHEMBL8896251 | 0.90 | TBXAS1 (0.52) | NPSR1TBXAS1TBXA2RUTS2RALDH1A1 | |
| SCHEMBL8895305 | 0.90 | UTS2R (0.46) | NPSR1TBXAS1TBXA2RUTS2RALDH1A1 | |
| SCHEMBL8418163 | 0.90 | TBXAS1 (0.49) | NPSR1TBXAS1TBXA2RUTS2RALDH1A1 | |
| SCHEMBL8896727 | 0.90 | NPSR1 (0.51) | NPSR1TBXAS1TBXA2RALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | claimed |
| CN-1244859-A | Benzenesulfonamide derivatives and drugs containing the same | HOKURIKU SEIYAKA CO LTD (JP) | 2000-02-16 | — | — | CN | disclosed |
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |