SCHEMBL8896383

SCHEMBL8896383

CC(C)CCCCC(NS(=O)(=O)c1ccc(Cl)cc1)c1ccc(CCCC(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.51
TBXAS1 P24557 12/20 0.49
TBXA2R P21731 5/20 0.49
UTS2R Q9UKP6 1/20 0.47
ALDH1A1 P00352 2/20 0.46
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8419341 0.98 NPSR1 (0.51) NPSR1TBXAS1TBXA2RUTS2RALDH1A1
SCHEMBL8898428 0.95 NPSR1 (0.50) NPSR1TBXAS1TBXA2RUTS2RALDH1A1
SCHEMBL8894801 0.95 NPSR1 (0.52) NPSR1TBXAS1TBXA2RUTS2RALDH1A1
SCHEMBL8418163 0.92 TBXAS1 (0.49) NPSR1TBXAS1TBXA2RUTS2RALDH1A1
SCHEMBL8897696 0.92 NPSR1 (0.51) NPSR1TBXAS1TBXA2RUTS2RALDH1A1
SCHEMBL8895793 0.91 TBXAS1 (0.50) NPSR1TBXAS1TBXA2RUTS2RALDH1A1
SCHEMBL8894922 0.91 TBXAS1 (0.50) NPSR1TBXAS1TBXA2RUTS2RALDH1A1
SCHEMBL8894873 0.91 TBXAS1 (0.50) NPSR1TBXAS1TBXA2RUTS2RALDH1A1
SCHEMBL8895059 0.91 TBXAS1 (0.50) NPSR1TBXAS1TBXA2RUTS2RALDH1A1
SCHEMBL8897096 0.91 TBXAS1 (0.52) NPSR1TBXAS1TBXA2RUTS2RALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0663392-A1 BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF HOKURIKU SEIYAKU CO., LTD. (JP) 1995-07-19 EP claimed
US-5597848-A PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS HOKURIKU SEIYAKU CO., LTD. (JP) 1997-01-28 US disclosed
EP-0663392-A1 BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF HOKURIKU SEIYAKU CO., LTD. (JP) 1995-07-19 EP disclosed