Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.67 |
| ▸ | DRD2 | P14416 | 5/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670782 | 0.87 | MTNR1A (0.51) | MTNR1AMTNR1BDRD2IDO1NQO2 | |
| SCHEMBL3417084 | 0.85 | HPGD (0.60) | HPGDKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL8479913 | 0.85 | CHRM2 (0.55) | DRD2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5786629 | 0.85 | NQO2 (0.52) | MTNR1AMTNR1BDRD2IDO1NQO2 | |
| Hydrochloric Acid SCHEMBL27897844 | 0.84 | HPGD (0.58) | HPGDKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL29242665 | 0.84 | NQO2 (0.54) | MTNR1AMTNR1BDRD2IDO1NQO2 | |
| SCHEMBL6874085 | 0.84 | NQO2 (0.51) | MTNR1AMTNR1BDRD2IDO1NQO2 | |
| SCHEMBL613087 | 0.83 | DRD2 (0.50) | MTNR1AMTNR1BDRD2NQO2HPGD | |
| SCHEMBL12434229 | 0.83 | KCNA5 (0.69) | MTNR1AMTNR1BIDO1HPGDKMT2A | |
| SCHEMBL8540588 | 0.83 | NQO2 (0.53) | MTNR1AMTNR1BDRD2IDO1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102056894-A | Homocysteine synthase inhibitor | MITSUBISHI TANABE PHARMA CORP | 2011-05-11 | — | — | CN | disclosed |
| US-5922697-A | Compounds, compositions and methods for inhibiting the binding of proteins containing an SH2 domain to cognate phosphorylated proteins | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | disclosed |
| WO-1997012903-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR INHIBITING THE BINDING OF PROTEINS CONTAINING AN SH2 DOMAIN TO COGNATE PHOSPHORYLATED PROTEINS | WARNER-LAMBERT COMPANY (US) | 1997-04-10 | — | — | WO | disclosed |