Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189421 | 0.78 | PLK1 (0.51) | PLK1PTGDR2L3MBTL1GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL8189425 | 0.74 | PLK1 (0.53) | PLK1PTGDR2L3MBTL1GAAALDH1A1 | |
| SCHEMBL10088967 | 0.72 | S1PR1 (0.42) | PLK1PTGDR2L3MBTL1GAAFFAR4 | |
| SCHEMBL8423057 | 0.69 | PLK1 (0.53) | PLK1L3MBTL1GAAALDH1A1MAPT | |
| SCHEMBL3054006 | 0.65 | PLK1 (0.68) | PLK1L3MBTL1GAAALDH1A1MAPT | |
| SCHEMBL9218012 | 0.65 | DAO (0.45) | — | |
| SCHEMBL5665614 | 0.63 | ELANE (0.44) | MAPTCYP1A2CYP2D6CYP2C19MEN1 | |
| SCHEMBL3495208 | 0.62 | MAPK14 (0.56) | PLK1L3MBTL1GAAALDH1A1MAPT | |
| SCHEMBL8672684 | 0.61 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL404394 | 0.61 | PLK1 (0.71) | PLK1L3MBTL1GAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944615-A1 | MICROBICIDAL AGENTS BASED ON THIOPHENE-2-CARBOXYLIC ACID DERIVATIVES | BAYER AG (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998023605-A1 | MICROBICIDAL AGENTS BASED ON THIOPHENE-2-CARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-04 | — | — | WO | disclosed |