SCHEMBL9218012

SCHEMBL9218012

O=C(Cl)Oc1cc(Cl)c(Cl)s1

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DAO P14920 3/20 0.45
GSK3B P49841 1/20 0.41
ABL1 P00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10883125 0.82 DAO (0.50) DAO
SCHEMBL8672684 0.70 ALDH1A1 (0.32) DAO
SCHEMBL8373375 0.69 GSK3B (0.43) GSK3B
SCHEMBL28742382 0.69
SCHEMBL1024697 0.68 F2 (0.43) DAOGSK3B
SCHEMBL8935123 0.67 DAO (0.68) DAOGSK3BABL1
SCHEMBL526115 0.67 BCL2L1 (0.50)
SCHEMBL10882465 0.65 DAO (0.55) DAO
SCHEMBL10998017 0.62 GSK3B (0.46) DAOGSK3BABL1
SCHEMBL11195574 0.62 DAO (0.45) DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450355-B1 Compounds for the combat against plant diseases DEGUSSA (DE) 1995-08-09 EP disclosed
EP-0450355-A1 Compounds for the combat against plant diseases Degussa Aktiengesellschaft (DE) 1991-10-09 EP disclosed
EP-0195201-B1 PROCESS FOR THE PREPARATION OF N-ACYL-2,3-DEHYDRO CARBOXYLIC ESTERS Degussa Aktiengesellschaft (DE) 1990-05-23 EP disclosed
EP-0195201-A2 Process for the preparation of N-acyl-2,3-dehydro carboxylic esters Degussa Aktiengesellschaft (DE) 1986-09-24 EP disclosed