Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
| ▸ | BHMT | Q93088 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200070 | 0.83 | BHMT (0.43) | BHMTSLC22A6CYP1A2CACNB3CACNA2D1 | |
| SCHEMBL24380113 | 0.82 | ACACB (0.44) | ACACBACACAACLYCYP2D6TSHR | |
| SCHEMBL9710087 | 0.81 | ACACB (0.47) | ACACBACACAACLYCYP2D6TSHR | |
| SCHEMBL6471049 | 0.79 | ACACB (0.47) | ACACBACACABHMTACLY | |
| SCHEMBL9514216 | 0.79 | ACACB (0.46) | ACACBACACAACLY | |
| SCHEMBL25436796 | 0.78 | BHMT (0.43) | BHMTSLC22A6CYP1A2ALDH1A1CACNB3 | |
| SCHEMBL19177 | 0.78 | CYP2D6 (0.36) | ACACBACACABHMTACLYCYP2D6 | |
| SCHEMBL3977531 | 0.78 | ACACB (0.50) | ACACBACACAACLYTSHRCYP1A2 | |
| SCHEMBL2718566 | 0.78 | ACACB (0.52) | ACACBACACAACLYCYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL8993648 | 0.77 | CYP2D6 (0.34) | ACACBACACABHMTACLYCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150259311-A1 | METHOD OF PRODUCING LACTONE FROM HYDROXYCARBOXYLIC ACID OR DICARBOXYLIC ACID IN AQUEOUS SOLUTION | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2015-09-17 | — | — | US | claimed |
| US-20130204015-A1 | PROCESS FOR PREPARING A LACTONE | RHODIA OPERATIONS (FR) | 2013-08-08 | — | — | US | claimed |
| CN-102834172-A | Method for preparing a lactone | RHODIA OPERATIONS | 2012-12-19 | — | — | CN | claimed |
| US-5856581-A | DECARBOXYLATING/CYCLIZING A DICARBOXYLIC ACID, IN LIQUID PHASE, IN THE PRESENCE OF A CATALYTICALLY EFFECTIVE AMOUNT OF A METAL OR COMPOUND COMPOUND THEREOF SELECTED FROM AMONG BORON, ALUMINUM, GALLIUM, INDIUM, THALLIUM, TIN, ANTIMONY, | RHONE-POULENC CHIMIE (FR) | 1999-01-05 | — | — | US | claimed |
| EP-0626364-B1 | Process for the preparation of a cyclic ketone | RHONE POULENC CHIMIE (FR) | 1998-04-08 | — | — | EP | claimed |
| EP-0626363-B1 | Process for the préparation of a cyclic ketone | RHONE POULENC CHIMIE (FR) | 1998-03-04 | — | — | EP | claimed |
| US-5600013-A | CATALYTIC CARBOXYLATION AND CYCLIZATION OF DICARBOXYLIC ACIDS | RHONE-POULENC CHIMIE (FR) | 1997-02-04 | — | — | US | claimed |
| US-20150259311-A1 | METHOD OF PRODUCING LACTONE FROM HYDROXYCARBOXYLIC ACID OR DICARBOXYLIC ACID IN AQUEOUS SOLUTION | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2015-09-17 | — | — | US | disclosed |
| US-20130204015-A1 | PROCESS FOR PREPARING A LACTONE | RHODIA OPERATIONS (FR) | 2013-08-08 | — | — | US | disclosed |
| CN-102834172-A | Method for preparing a lactone | RHODIA OPERATIONS | 2012-12-19 | — | — | CN | disclosed |
| US-5856581-A | DECARBOXYLATING/CYCLIZING A DICARBOXYLIC ACID, IN LIQUID PHASE, IN THE PRESENCE OF A CATALYTICALLY EFFECTIVE AMOUNT OF A METAL OR COMPOUND COMPOUND THEREOF SELECTED FROM AMONG BORON, ALUMINUM, GALLIUM, INDIUM, THALLIUM, TIN, ANTIMONY, | RHONE-POULENC CHIMIE (FR) | 1999-01-05 | — | — | US | disclosed |
| US-5600013-A | CATALYTIC CARBOXYLATION AND CYCLIZATION OF DICARBOXYLIC ACIDS | RHONE-POULENC CHIMIE (FR) | 1997-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130204015-A1 | PROCESS FOR PREPARING A LACTONE | HSD17B7, HSD17B3, RPS3 | ACACB 1187/4885ACACA 686/4885BHMT 3493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.