Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RPA1 | P27694 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420064 | 0.90 | SMN1; SMN2 (0.62) | PTGS2SMN1; SMN2CHRNA7PTGS1MAPK9 | |
| SCHEMBL8423812 | 0.82 | PTGS2 (0.54) | PTGS2SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL28190691 | 0.80 | KMT2A (0.62) | MEN1KMT2AMAPTPTGS1L3MBTL1 | |
| SCHEMBL28191259 | 0.79 | MAPT (0.55) | ALOX5SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL9049040 | 0.78 | PTGS2 (0.67) | PTGS2ALOX5SMN1; SMN2PTGS1RPA1 | |
| SCHEMBL8422302 | 0.78 | PTGS2 (0.70) | PTGS2SMN1; SMN2CHRNA7PTGS1 | |
| SCHEMBL8420828 | 0.78 | PTGS2 (0.80) | PTGS2ALOX5PTGS1 | |
| SCHEMBL8421185 | 0.78 | PTGS2 (0.80) | PTGS2ALOX5PTGS1 | |
| SCHEMBL3866506 | 0.78 | SMN1; SMN2 (0.82) | PTGS2SMN1; SMN2CHRNA7RPA1MALT1 | |
| SCHEMBL7156590 | 0.78 | MALT1 (0.58) | SMN1; SMN2MEN1KMT2AL3MBTL1RPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |