Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MARS1 | P56192 | 2/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422270 | 0.95 | PTGS2 (0.48) | PTGS2PTGS1CYP2C9MARS1CHRNA7 | |
| SCHEMBL8733829 | 0.92 | PTGS2 (0.54) | PTGS2PTGS1CYP2C9MARS1MAPK9 | |
| SCHEMBL8421778 | 0.92 | PTGS2 (0.56) | PTGS2PTGS1CYP2C9CHRNA7MAPK9 | |
| SCHEMBL8423598 | 0.91 | PTGS2 (0.47) | PTGS2PTGS1CYP2C9CHRNA7MAPK9 | |
| SCHEMBL8421736 | 0.90 | PTGS2 (0.46) | PTGS2PTGS1CYP2C9MAPK9PDPK1 | |
| SCHEMBL8420738 | 0.90 | PTGS2 (0.46) | PTGS2PTGS1CYP2C9MAPK9PDPK1 | |
| SCHEMBL8424146 | 0.90 | PTGS2 (0.46) | PTGS2PTGS1CYP2C9MARS1CHRNA7 | |
| SCHEMBL8422283 | 0.90 | CYP2C9 (0.49) | PTGS2PTGS1CYP2C9CHRNA7 | |
| SCHEMBL8420838 | 0.89 | PTGS2 (0.48) | PTGS2PTGS1CYP2C9MAPK9PDPK1 | |
| SCHEMBL8422379 | 0.88 | PTGS2 (0.47) | PTGS2PTGS1CYP2C9MAPK9PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |