Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | F7 | P08709 | 2/20 | 0.41 |
| ▸ | F3 | P13726 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816992 | 0.84 | F2 (0.41) | F2PRSS1F7F3PRSS2 | |
| SCHEMBL7817575 | 0.76 | F2 (0.61) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7405928 | 0.76 | F2 (0.61) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8418959 | 0.76 | F2 (0.61) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7817431 | 0.76 | F2 (0.61) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8420322 | 0.74 | F2 (0.61) | F2PRSS1MAPK1PRSS2PRSS3 | |
| SCHEMBL7818207 | 0.74 | F2 (0.47) | F2PRSS1PRSS2PRSS3L3MBTL1 | |
| SCHEMBL7505080 | 0.74 | F2 (0.61) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7404488 | 0.74 | F2 (0.61) | F2PRSS1MAPK1PRSS2PRSS3 | |
| SCHEMBL7819971 | 0.73 | F2 (0.44) | F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866573-A | Pyrazinone thrombin inhibitors | MERCK & CO., INC. (US) | 1999-02-02 | — | — | US | disclosed |