Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420707 | 0.69 | MAOB (0.43) | CA12CA9CA1CA2MAOB | |
| SCHEMBL8420073 | 0.68 | CA12 (0.54) | CA12CA9CA1CA2MAOB | |
| SCHEMBL5711170 | 0.68 | CA12 (0.54) | CA12CA9CA1CA2MAOB | |
| SCHEMBL2105292 | 0.67 | CA12 (0.50) | CA12CA9CA1CA2MAOB | |
| SCHEMBL8179958 | 0.66 | MEN1 (0.53) | CA12CA9CA1CA2MAOB | |
| SCHEMBL8178252 | 0.66 | CA12 (0.51) | CA12CA9CA1CA2MAOB | |
| SCHEMBL8419930 | 0.65 | CA12 (0.44) | CA12CA9CA1CA2MAOB | |
| SCHEMBL8381918 | 0.65 | MAOB (0.51) | CA12CA9CA1CA2MAOB | |
| SCHEMBL4013115 | 0.65 | MAOB (0.55) | CA12CA9CA1CA2MAOB | |
| SCHEMBL27922627 | 0.65 | MAOB (0.51) | CA12CA9CA1CA2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872139-A | MUSCLE RELAXANTS USED TO TREAT URINARY INCONTINENCE, IRRITABLE BOWEL SYNDROME, ASTHMA, PREMATURE LABOR, CONGESTIVE HEART FAILURE, ANGINA, CEREBRAL VASCULAR DISEASE AND HYPERTENSION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-02-16 | — | — | US | claimed |
| US-5872139-A | MUSCLE RELAXANTS USED TO TREAT URINARY INCONTINENCE, IRRITABLE BOWEL SYNDROME, ASTHMA, PREMATURE LABOR, CONGESTIVE HEART FAILURE, ANGINA, CEREBRAL VASCULAR DISEASE AND HYPERTENSION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-02-16 | — | — | US | disclosed |