Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.57 |
| ▸ | TUBB | P07437 | 1/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28338665 | 0.98 | HPGD (0.61) | KDM4EALDH1A1HPGDFYNTUBB4A | |
| SCHEMBL28238880 | 0.87 | FYN (0.60) | KDM4EALDH1A1HPGDFYNTUBB4A | |
| SCHEMBL721861 | 0.85 | ACHE (0.65) | KDM4EALDH1A1HPGDFYNCA9 | |
| SCHEMBL10702893 | 0.82 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDFYNTUBB4A | |
| SCHEMBL28972511 | 0.82 | CA12 (0.46) | KDM4EALDH1A1HPGDFYNCA9 | |
| SCHEMBL5040305 | 0.82 | ERN1 (0.59) | — | |
| SCHEMBL14097284 | 0.80 | FYN (0.59) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| Aucuparin SCHEMBL11223391 | 0.80 | SMPD3 (0.57) | KDM4ECA9CA12CA1CA2 | |
| SCHEMBL21608966 | 0.80 | CA12 (0.44) | KDM4EALDH1A1HPGDFYNCA9 | |
| SCHEMBL28972669 | 0.80 | CA12 (0.44) | KDM4EALDH1A1HPGDFYNCA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955257-A | Preparation and lipid lowering application of 2' -methoxyaucuparin | 大理大学 | 2024-11-15 | — | — | CN | claimed |
| CN-118955257-A | Preparation and lipid lowering application of 2' -methoxyaucuparin | 大理大学 | 2024-11-15 | — | — | CN | disclosed |
| CN-118955257-A | Preparation and lipid lowering application of 2' -methoxyaucuparin | 大理大学 | 2024-11-15 | — | — | CN | disclosed |
| CN-117050075-A | Biaryl ring BET inhibitor and synthetic method and application thereof | 中国药科大学 | 2023-11-14 | — | — | CN | disclosed |
| CN-115490607-A | C 2 Synthesis method of-symmetrical chiral aryl iodide catalyst | 南通大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-114773249-A | Compounds, pharmaceutical compositions and methods for treating inflammatory diseases | 艾匹克治疗公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-112961041-B | Catechol compound and preparation method and application thereof | 心远(广州)药物研究有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-113372201-A | Preparation method of biphenol compound and derivatives thereof | 中国中医科学院中药研究所 | 2021-09-10 | — | — | CN | disclosed |
| EP-1057815-B1 | CYCLIC AMIDE COMPOUNDS | KOWA CO (JP) | 2007-09-05 | — | — | EP | disclosed |
| EP-0770116-B1 | DIARYL-2H-NAPHTHOPYRANES | RODENSTOCK OPTIK G (DE) | 1999-09-22 | — | — | EP | disclosed |
| EP-0770116-A1 | DIARYL-2H-NAPHTHOPYRANES | Optische Werke G. Rodenstock (DE) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996001884-A1 | DIARYL-2H-NAPHTHOPYRANES | OPTISCHE WERKE G. RODENSTOCK (DE) | 1996-01-25 | — | — | WO | disclosed |
| CN-85105299-A | The preparation method of cephem compounds | — | 1987-01-07 | — | — | CN | disclosed |