Ethylene Glycol

Ethylene Glycol

SCHEMBL8420849

O=C(O)c1ccc(N2C(=O)C=CC2=O)cc1.O=C(O)c1ccc(N2C(=O)C=CC2=O)cc1.OCCO

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 1/20 0.85
NSD2 O96028 1/20 0.56
G6PD P11413 1/20 0.56
KEAP1 Q14145 1/20 0.56
NFE2L2 Q16236 1/20 0.56
MGLL Q99685 8/20 0.56
FAAH O00519 5/20 0.56
CA12 O43570 6/20 0.55
CA9 Q16790 6/20 0.55
CA1 P00915 5/20 0.55
HSP90AA1 P07900 2/20 0.54
NPSR1 Q6W5P4 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
ALDH1A1 P00352 1/20 0.54
HPGD P15428 1/20 0.54
HTT P42858 1/20 0.54
CACNA1B Q00975 1/20 0.54
APBA1 Q02410 1/20 0.54
PKM P14618 1/20 0.52
MAPK1 P28482 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235166 0.92 DDAH1 (1.00) DDAH1NSD2G6PDKEAP1NFE2L2
Alcohol SCHEMBL29133199 0.91 DDAH1 (0.82) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL1822680 0.90 DDAH1 (0.96) DDAH1NSD2G6PDKEAP1NFE2L2
Hydrochloric Acid SCHEMBL9278333 0.90 DDAH1 (0.96) DDAH1NSD2G6PDKEAP1NFE2L2
Maleic Anhydride SCHEMBL8720551 0.82 DDAH1 (0.79) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL11667624 0.82 DDAH1 (0.79) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL15082451 0.80 DDAH1 (0.76) DDAH1NSD2G6PDKEAP1NFE2L2
Tetrahydrofuran SCHEMBL5208313 0.80 DDAH1 (0.74) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL331470 0.78 DDAH1 (0.73) DDAH1NSD2G6PDKEAP1NFE2L2
Terephthalic Acid SCHEMBL319125 0.77 TSHR (0.75) CA12CA9CA1ALDH1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001958-A POLYMER HAS ON AT LEAST TWO OF ITS ENDS, AT LEAST ONE REACTIVE END GROUP OF A DIFFERENT CHEMICAL TYPE FROM THAT OF THE GROUP PREDOMINANTLY USED IN POLYMERIZATION AND THE PREPARATION OF A POLYMER SKELETON. FLAMEL TECHNOLOGIES (FR) 1999-12-14 US disclosed