Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574136 | 1.00 | TSHR (0.55) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL9641955 | 0.97 | TSHR (0.52) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL1658068 | 0.97 | TSHR (0.52) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL9724988 | 0.97 | TSHR (0.52) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL3368771 | 0.97 | TSHR (0.52) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL345866 | 0.97 | TSHR (0.52) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL6158105 | 0.97 | TSHR (0.52) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL366532 | 0.97 | TSHR (0.52) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL7784084 | 0.97 | TSHR (0.52) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL6157071 | 0.97 | TSHR (0.52) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000432-B2 | Processes for the synthesis of chiral 1-alkanols | PURDUE RESEARCH FOUNDATION (US) | 2018-06-19 | — | — | US | disclosed |
| US-10000432-B2 | Processes for the synthesis of chiral 1-alkanols | PURDUE RESEARCH FOUNDATION (US) | 2018-06-19 | — | — | US | disclosed |
| US-20160332940-A1 | PROCESSES FOR THE SYNTHESIS OF CHIRAL 1-ALKANOLS | PURDUE RESEARCH FOUNDATION (US) | 2016-11-17 | — | — | US | disclosed |
| US-20160332940-A1 | PROCESSES FOR THE SYNTHESIS OF CHIRAL 1-ALKANOLS | PURDUE RESEARCH FOUNDATION (US) | 2016-11-17 | — | — | US | disclosed |
| US-6002037-A | INTERMEDIATES OF CHIRAL ORGANIC COMPOUNDS, E.G., ISOALKYL ALCOHOLS, IN HIGHLY ENANTIOMERIC EXCESS FOR PREPARING VITAMINS, DRUGS AND BIOMOLECULES; METALLOCENE CATALYSTS | PURDUE RESEARCH FOUNDATION (US) | 1999-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160332940-A1 | PROCESSES FOR THE SYNTHESIS OF CHIRAL 1-ALKANOLS | CYP51A1, ALKBH3, ALKBH1 | TSHR 4338/4885SMN1; SMN2 4633/4885LMNA 3812/4885 |
| US-10000432-B2 | Processes for the synthesis of chiral 1-alkanols | CYP51A1, ALKBH3, ALKBH1 | TSHR 4338/4885SMN1; SMN2 4633/4885LMNA 3812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.