SCHEMBL345866

SCHEMBL345866

CCCC(C)CCCCCCCCCCO

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
LMNA P02545 5/20 0.50
ALDH1A1 P00352 2/20 0.50
HSD17B10 Q99714 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
ACE2 Q9BYF1 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
PRKD3 O94806 1/20 0.41
PRKCG P05129 1/20 0.41
PRKCB P05771 1/20 0.41
PRKCA P17252 1/20 0.41
PRKCH P24723 1/20 0.41
PRKCI P41743 1/20 0.41
PRKCE Q02156 1/20 0.41
PRKCQ Q04759 1/20 0.41
PRKCZ Q05513 1/20 0.41
PRKCD Q05655 1/20 0.41
PRKD1 Q15139 1/20 0.41
SPHK1 Q9NYA1 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6442377 1.00 TSHR (0.52) TSHRLMNAALDH1A1HSD17B10MEN1
SCHEMBL366532 1.00 TSHR (0.52) TSHRLMNAALDH1A1HSD17B10MEN1
SCHEMBL9724988 1.00 TSHR (0.52) TSHRLMNAALDH1A1HSD17B10MEN1
SCHEMBL9641955 1.00 TSHR (0.52) TSHRLMNAALDH1A1HSD17B10MEN1
SCHEMBL7784084 1.00 TSHR (0.52) TSHRLMNAALDH1A1HSD17B10MEN1
SCHEMBL3368771 1.00 TSHR (0.52) TSHRLMNAALDH1A1HSD17B10MEN1
SCHEMBL6157071 1.00 TSHR (0.52) TSHRLMNAALDH1A1HSD17B10MEN1
SCHEMBL6158105 1.00 TSHR (0.52) TSHRLMNAALDH1A1HSD17B10MEN1
SCHEMBL1658068 1.00 TSHR (0.52) TSHRLMNAALDH1A1HSD17B10MEN1
SCHEMBL3369390 1.00 TSHR (0.52) TSHRLMNAALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8603449-B2 Rinse-off conditioning composition comprising a near-terminal branched alcohol THE PROCTER & GAMBLE COMPANY (US) 2013-12-10 US claimed
EP-2593073-A2 RINSE-OFF CONDITIONING COMPOSITION COMPRISING A NEAR-TERMINAL BRANCHED ALCOHOL The Procter and Gamble Company (US) 2013-05-22 EP claimed
US-20120014901-A1 Rinse-Off Conditioning Composition Comprising a Near-Terminal Branched Alcohol THE PROCTER & GAMBLE COMPANY 2012-01-19 US claimed
WO-2012009522-A2 RINSE-OFF CONDITIONING COMPOSITION COMPRISING A NEAR-TERMINAL BRANCHED ALCOHOL THE PROCTER & GAMBLE COMPANY (US) 2012-01-19 WO claimed
US-8883698-B2 Compositions comprising a near terminal-branched compound and methods of making the same THE PROCTER & GAMBLE CO (US) 2014-11-11 US disclosed
US-8765651-B2 Method of cleansing hair THE PROCTER & GAMBLE COMPANY (US) 2014-07-01 US disclosed
US-8603449-B2 Rinse-off conditioning composition comprising a near-terminal branched alcohol THE PROCTER & GAMBLE COMPANY (US) 2013-12-10 US disclosed
CN-103228252-A Compositions comprising a near terminal-ranched compound and methods of making the same PROCTER & GAMBLE 2013-07-31 CN disclosed
EP-2593080-A2 METHOD OF CLEANSING HAIR The Procter and Gamble Company (US) 2013-05-22 EP disclosed
EP-2593073-A2 RINSE-OFF CONDITIONING COMPOSITION COMPRISING A NEAR-TERMINAL BRANCHED ALCOHOL The Procter and Gamble Company (US) 2013-05-22 EP disclosed
EP-2593074-A2 COMPOSITIONS COMPRISING A NEAR TERMINAL-BRANCHED COMPOUND AND METHODS OF MAKING THE SAME The Procter and Gamble Company (US) 2013-05-22 EP disclosed
EP-2593075-A2 A PERSONAL CARE COMPOSITION COMPRISING A NEAR-TERMINAL BRANCHED COMPOUND The Procter and Gamble Company (US) 2013-05-22 EP disclosed
US-20130053300-A1 Compositions Comprising A Near Terminal-Branched Compound And Methods Of Making The Same THE PROCTER & GAMBLE COMPANY 2013-02-28 US disclosed
US-20120012130-A1 Method of Cleansing Hair THE PROCTER & GAMBLE COMPANY 2012-01-19 US disclosed
US-20120014900-A1 Personal Care Composition Comprising a Near-Terminal Branched Compound THE PROCTER & GAMBLE COMPANY 2012-01-19 US disclosed
US-20120014901-A1 Rinse-Off Conditioning Composition Comprising a Near-Terminal Branched Alcohol THE PROCTER & GAMBLE COMPANY 2012-01-19 US disclosed
WO-2012009522-A2 RINSE-OFF CONDITIONING COMPOSITION COMPRISING A NEAR-TERMINAL BRANCHED ALCOHOL THE PROCTER & GAMBLE COMPANY (US) 2012-01-19 WO disclosed
WO-2012009539-A2 METHOD OF CLEANSING HAIR THE PROCTER & GAMBLE COMPANY (US) 2012-01-19 WO disclosed
WO-2012009523-A2 A PERSONAL CARE COMPOSITION COMPRISING A NEAR-TERMINAL BRANCHED COMPOUND THE PROCTER & GAMBLE COMPANY (US) 2012-01-19 WO disclosed
WO-2012009525-A2 COMPOSITIONS COMPRISING A NEAR TERMINAL-BRANCHED COMPOUND AND METHODS OF MAKING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2012-01-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120012130-A1 Method of Cleansing Hair POLR1C, SHH, LATS2 TSHR 2509/4885LMNA 2064/4885ALDH1A1 513/4885
US-20120014900-A1 Personal Care Composition Comprising a Near-Terminal Branched Compound CUTA, KRT18, PARN TSHR 2911/4885LMNA 826/4885ALDH1A1 664/4885
US-20120014901-A1 Rinse-Off Conditioning Composition Comprising a Near-Terminal Branched Alcohol ITGB7, ARG1, ITGB1 TSHR 3671/4885LMNA 296/4885ALDH1A1 894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.