SCHEMBL8420960

SCHEMBL8420960

O=C(OCC1=CCCCC1)C1=CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 2/20 0.44
HDAC2 Q92769 2/20 0.44
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
CTSK P43235 1/20 0.41
ALDH1A1 P00352 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
HPGD P15428 2/20 0.38
LMNA P02545 1/20 0.38
ALOX12 P18054 1/20 0.38
RAB9A P51151 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8014754 0.83 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2HPGDLMNAALOX12
SCHEMBL10552076 0.82 HDAC4 (0.50) HDAC4HDAC2HDAC8HDAC6CTSK
SCHEMBL5267846 0.82 TAAR1 (0.41) ALDH1A1SMN1; SMN2HPGDLMNARAB9A
SCHEMBL10765456 0.82 SMN1; SMN2 (0.43) ALDH1A1SMN1; SMN2HPGDLMNARAB9A
SCHEMBL5266129 0.80 TAAR1 (0.43) ALDH1A1SMN1; SMN2HPGDLMNARAB9A
SCHEMBL6049107 0.80 HDAC4 (0.48) HDAC4HDAC2HDAC8HDAC6CTSK
SCHEMBL21306553 0.79 CES2 (0.53) ALDH1A1SMN1; SMN2HPGDLMNAALOX12
SCHEMBL8479323 0.79 TDP1 (0.53) HDAC4HDAC2HDAC8HDAC6ALDH1A1
SCHEMBL22975403 0.79 HDAC4 (0.47) HDAC4HDAC2HDAC8HDAC6CTSK
SCHEMBL22324339 0.79 HDAC4 (0.47) HDAC4HDAC2HDAC8HDAC6CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5962586-A Epoxy resin(s) with anhydride and polybutadiene-maleic anhydride adduct HARPER JOHN D (US) 1999-10-05 US claimed
US-5629379-A Anhydride-hardened epoxy resin with polybutadiene-maleic anhydride adduct HARPER JOHN D (US) 1997-05-13 US claimed
US-4142991-A TITANIUM TRICHLORIDE STAUFFER CHEMICAL COMPANY (US) 1979-03-06 US claimed
CN-102574983-B Curable resin composition and cured products thereof NIPPON KAYAKU KK 2015-07-08 CN disclosed
CN-102971355-B Polyvalent carboxylic acid composition, curing agent composition, and curable resin composition containing polyvalent carboxylic acid composition or curing agent composition as curing agent for epoxy resin NIPPON KAYAKU KK 2015-07-08 CN disclosed
CN-102395555-B Epoxy resin, curable resin composition, and material resulting from curing same NIPPON KAYAKU KK 2015-01-21 CN disclosed
CN-102333768-B diene compound, epoxy resin and composition thereof NIPPON KAYAKU KK 2014-11-12 CN disclosed
CN-102388016-B Olefin compound, epoxy resin, curable resin composition and cured product thereof, and led device NIPPON KAYAKU KK 2013-11-06 CN disclosed
CN-102971355-A Polyvalent carboxylic acid composition, curing agent composition, and curable resin composition containing polyvalent carboxylic acid composition or curing agent composition as curing agent for epoxy resin NIPPON KAYAKU KK 2013-03-13 CN disclosed
CN-102574983-A Curable resin composition and cured products thereof NIPPON KAYAKU KK 2012-07-11 CN disclosed
CN-102395555-A Olefin resin, epoxy resin, curable resin composition, and material resulting from curing same NIPPON KAYAKU KK 2012-03-28 CN disclosed
US-4124530-A TITANIUM TRICHLORIDE STAUFFER CHEMICAL COMPANY (US) 1978-11-07 US disclosed
US-4086303-A FIRE RETARDANTS STAUFFER CHEMICAL COMPANY (US) 1978-04-25 US disclosed
US-4013814-A FIREPROOFING POLYURETHANES AND CELLULOSE ACETATES STAUFFER CHEMICAL COMPANY (US) 1977-03-22 US disclosed
US-4012463-A B-HALOALKYL ESTER OF PH3SPHORUS ACID STAUFFER CHEMICAL COMPANY (US) 1977-03-15 US disclosed
US-4005034-A Poly(haloethyl-ethyleneoxy) phosphoric acid ester polymers as flame retardant agents STAUFFER CHEMICAL COMPANY (US) 1977-01-25 US disclosed
US-3959415-A Methods of preparing stable condensation products and products therefrom using an alkylene oxide treatment STAUFFER CHEMICAL COMPANY (US) 1976-05-25 US disclosed
US-3959414-A Method of preparing stable condensation products using a water-alkylene oxide treatment and products therefrom STAUFFER CHEMICAL COMPANY (US) 1976-05-25 US disclosed
US-3956431-A Process for forming phosphonate polymers STAUFFER CHEMICAL COMPANY (US) 1976-05-11 US disclosed
US-3954917-A B-HALOALKYL ESTERS OF PHOSPHOROUS ACID STAUFFER CHEMICAL COMPANY (US) 1976-05-04 US disclosed