SCHEMBL842154

SCHEMBL842154

O=S(=O)(O)c1cc(S(=O)(=O)O)c(Cl)c(O)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGAM1 P18669 1/20 0.42
HSD17B10 Q99714 4/20 0.40
CASP1 P29466 2/20 0.40
ALDH1A1 P00352 1/20 0.40
CASP7 P55210 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NSD2 O96028 1/20 0.39
MMP14 P50281 1/20 0.39
CASP6 P55212 1/20 0.39
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
NQO1 P15559 1/20 0.35
ING2 Q9H160 1/20 0.34
CASR P41180 5/20 0.33
HPGD P15428 3/20 0.33
TSHR P16473 2/20 0.33
CA4 P22748 1/20 0.33
BRD4 O60885 1/20 0.32
MAPK1 P28482 1/20 0.31
MPL P40238 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL843141 0.98 PGAM1 (0.41) PGAM1HSD17B10CASP1ALDH1A1CASP7
SCHEMBL9150239 0.86 HSD17B10 (0.42) PGAM1HSD17B10CASP1ALDH1A1CASP7
SCHEMBL27639479 0.84 HSD17B10 (0.48) PGAM1HSD17B10CASP1ALDH1A1CASP7
SCHEMBL31251954 0.84 HSD17B10 (0.48) PGAM1HSD17B10CASP1ALDH1A1CASP7
SCHEMBL1224928 0.83 PGAM1 (0.53) PGAM1HSD17B10CASP1ALDH1A1CASP7
SCHEMBL28145555 0.80 PGAM1 (0.52) PGAM1HSD17B10CASP1ALDH1A1CASP7
SCHEMBL28146678 0.80 PGAM1 (0.52) PGAM1HSD17B10CASP1ALDH1A1CASP7
SCHEMBL11100105 0.80 CA1 (0.43) HSD17B10CASP1ALDH1A1CASP7TDP1
SCHEMBL11356717 0.78 PRMT1 (0.39) PGAM1HSD17B10CASP1ALDH1A1CASP7
SCHEMBL6690314 0.76 CA1 (0.35) HSD17B10CASP1ALDH1A1CASP7TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2722101-B1 REVERSE-OSMOSIS MEMBRANE HAVING AN ULTRA-HYDROPHILIC PROTECTIVE LAYER AND METHOD FOR PRODUCING SAME LG CHEMICAL LTD (KR) 2018-10-24 EP claimed
CN-103328080-B Comprise the reverse osmosis membrane of super hydrophilic passivation layer and manufacture the method for this reverse osmosis membrane LG CHEM, LTD. (KR) 2016-01-13 CN claimed
US-8770414-B2 Reverse osmosis membrane including ultra-hydrophilic passivation layer and method of manufacturing the same LG CHEM, LTD. (KR) 2014-07-08 US claimed
EP-2722101-A2 REVERSE-OSMOSIS MEMBRANE HAVING AN ULTRA-HYDROPHILIC PROTECTIVE LAYER AND METHOD FOR PRODUCING SAME LG Chem, Ltd. (KR) 2014-04-23 EP claimed
US-20130284663-A1 REVERSE OSMOSIS MEMBRANE INCLUDING ULTRA-HYDROPHILIC PASSIVATION LAYER AND METHOD OF MANUFACTURING THE SAME LG CHEM, LTD. (KR) 2013-10-31 US claimed
US-8142953-B2 Hydrophilic adjuvant LG CHEM, LTD. (KR) 2012-03-27 US claimed
US-20100167168-A1 Hydrophilic Adjuvant LG CHEM, LTD. (KR) 2010-07-01 US claimed
WO-2007069867-A1 HYDROPHILIC ADJUVANT LG CHEM, LTD (KR) 2007-06-21 WO claimed
EP-2722101-B1 REVERSE-OSMOSIS MEMBRANE HAVING AN ULTRA-HYDROPHILIC PROTECTIVE LAYER AND METHOD FOR PRODUCING SAME LG CHEMICAL LTD (KR) 2018-10-24 EP disclosed
CN-103328080-B Comprise the reverse osmosis membrane of super hydrophilic passivation layer and manufacture the method for this reverse osmosis membrane LG CHEM, LTD. (KR) 2016-01-13 CN disclosed
US-8770414-B2 Reverse osmosis membrane including ultra-hydrophilic passivation layer and method of manufacturing the same LG CHEM, LTD. (KR) 2014-07-08 US disclosed
EP-2722101-A2 REVERSE-OSMOSIS MEMBRANE HAVING AN ULTRA-HYDROPHILIC PROTECTIVE LAYER AND METHOD FOR PRODUCING SAME LG Chem, Ltd. (KR) 2014-04-23 EP disclosed
US-20130284663-A1 REVERSE OSMOSIS MEMBRANE INCLUDING ULTRA-HYDROPHILIC PASSIVATION LAYER AND METHOD OF MANUFACTURING THE SAME LG CHEM, LTD. (KR) 2013-10-31 US disclosed
US-8142953-B2 Hydrophilic adjuvant LG CHEM, LTD. (KR) 2012-03-27 US disclosed
US-20100167168-A1 Hydrophilic Adjuvant LG CHEM, LTD. (KR) 2010-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100167168-A1 Hydrophilic Adjuvant CD44, CD74, LY96 PGAM1 3086/4885HSD17B10 1930/4885CASP1 4367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.