SCHEMBL842155

SCHEMBL842155

C=C[Si](C)(O[Si](O[Si](C)(C=C)c1ccccc1)(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19398250 0.98 ESR1 (0.31) ESR1ESR2
SCHEMBL12032191 0.93
SCHEMBL94078 0.90 ESR1 (0.35) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL6889166 0.88 ESR1 (0.34) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL28879222 0.86 ESR1 (0.33) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL9900064 0.86 ESR1 (0.33) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL12032189 0.86 ESR1 (0.33) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL13038467 0.84 ESR1 (0.32) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL15544196 0.84 ESR1 (0.32) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL31344407 0.84 ESR1 (0.32) ESR1ESR2ALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9862803-B2 Branched organopolysiloxane and a method for preparing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
US-9657175-B2 Silicone resin composition for sealing optical semiconductor element and optical semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-23 US disclosed
US-9657175-B2 Silicone resin composition for sealing optical semiconductor element and optical semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-23 US disclosed
US-20160304675-A1 BRANCHED ORGANOPOLYSILOXANE AND A METHOD FOR PREPARING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-10-20 US disclosed
US-20160108240-A1 SILICONE RESIN COMPOSITION FOR SEALING OPTICAL SEMICONDUCTOR ELEMENT AND OPTICAL SEMICONDUCTOR DEVICE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-04-21 US disclosed
US-20160108240-A1 SILICONE RESIN COMPOSITION FOR SEALING OPTICAL SEMICONDUCTOR ELEMENT AND OPTICAL SEMICONDUCTOR DEVICE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-04-21 US disclosed
US-8637627-B2 Phenoxyphenyl polysiloxane composition and method for making and using same ROHM AND HAAS COMPANY (US) 2014-01-28 US disclosed
US-8142895-B2 Heat stable aryl polysiloxane compositions ROHM AND HAAS COMPANY (US) 2012-03-27 US disclosed
US-8029904-B2 Aryl (thio)ether aryl polysiloxane composition and methods for making and using same ROHM AND HAAS COMPANY (US) 2011-10-04 US disclosed
EP-1927636-B1 Aryl(thio)ether aryl polysiloxane composition and methods for making and using same ROHM & HAAS (US) 2010-02-10 EP disclosed
US-20090146324-A1 Phenoxyphenyl polysiloxane composition and method for making and using same ROHM AND HAAS COMPANY (US) 2009-06-11 US disclosed
US-20080160323-A1 Hydrosilation catalysts; for encapsulating semiconductors U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2008-07-03 US disclosed
EP-1927636-A1 Aryl(thio)ether aryl polysiloxane composition and methods for making and using same Rohm and Haas Company (US) 2008-06-04 EP disclosed
EP-1914262-A1 Heat stable aryl polysiloxane compositions Rohm and Haas Company (US) 2008-04-23 EP disclosed
US-20080090986-A1 Cured; encapsulated semiconductors; alkylene bridged aryl polysiloxane and hydrosilation catalysts; heating, aging; discoloration inhibition U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2008-04-17 US disclosed