SCHEMBL8421908

SCHEMBL8421908

Nc1ccc2[nH]nnc2c1.[Ag]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.47
KDM4E B2RXH2 6/20 0.42
MAPT P10636 6/20 0.42
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
ALDH1A1 P00352 3/20 0.42
GAA P10253 3/20 0.42
RAB9A P51151 3/20 0.42
HPGD P15428 2/20 0.42
ROCK2 O75116 1/20 0.42
ROCK1 Q13464 1/20 0.42
HIF1A Q16665 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPKAPK2 P49137 1/20 0.42
RPS6KA3 P51812 1/20 0.42
CSNK2A1 P68400 1/20 0.42
PLK3 Q9H4B4 1/20 0.42
HTT P42858 3/20 0.40
F2 P00734 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL111984 0.98 DYRK1A (0.48) DYRK1AKDM4EMAPTMEN1KMT2A
Fluoride SCHEMBL31379737 0.96 DYRK1A (0.47) DYRK1AKDM4EMAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL10929282 0.96 DYRK1A (0.47) DYRK1AKDM4EMAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL2493619 0.96 DYRK1A (0.47) DYRK1AKDM4EMAPTMEN1KMT2A
Sulfuric Acid SCHEMBL29043410 0.87 ALDH1A1 (0.41) DYRK1AKDM4EMAPTMEN1KMT2A
SCHEMBL6199433 0.82 MAPT (0.70) DYRK1AKDM4EMAPTMEN1KMT2A
SCHEMBL735804 0.81 PRKCI (0.48) DYRK1AKDM4EMAPTMEN1KMT2A
Tert-Butyl Formate SCHEMBL28057004 0.79 TDP1 (0.37) DYRK1AKDM4EMAPTMEN1KMT2A
SCHEMBL13711422 0.78 MAPT (0.47) DYRK1AKDM4EMAPTMEN1KMT2A
SCHEMBL19640293 0.76 CLK1 (0.34) DYRK1AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573048-B1 A method of image formation KONISHIROKU PHOTO IND (JP) 1999-10-20 EP disclosed
EP-0190054-B2 Heat-processable color photosensitive material KONISHIROKU PHOTO IND (JP) 1994-01-12 EP disclosed
EP-0573048-A2 A method of image formation KONICA CORPORATION (JP) 1993-12-08 EP disclosed
EP-0190512-B1 POSITIVE IMAGE FORMING METHOD KONICA CORPORATION (JP) 1992-09-30 EP disclosed
EP-0256820-B1 THERMAL DEVELOPING LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1992-07-29 EP disclosed
US-5071740-A HEAT DEVELOPABLE COLOR PHOTOSENSITIVE MATERIAL KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1991-12-10 US disclosed
US-5032499-A High density, stability KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1991-07-16 US disclosed
US-4868089-A ANHYDROUS HEAT TREATMENT TO INCREASE SENSITIVITY OF SILVER HALIDE EMULSION KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-09-19 US disclosed
EP-0190054-B1 HEAT-PROCESSABLE COLOR PHOTOSENSITIVE MATERIAL KONICA CORPORATION (JP) 1989-04-19 EP disclosed
EP-0256820-A2 Thermal developing light-sensitive material KONICA CORPORATION (JP) 1988-02-24 EP disclosed
EP-0190512-A2 Positive image forming method KONICA CORPORATION (JP) 1986-08-13 EP disclosed
EP-0190054-A2 Heat-processable color photosensitive material KONICA CORPORATION (JP) 1986-08-06 EP disclosed
US-4543309-A BENZOTRIAZOLE SILVER SALT, REDUCING AGENT, BINDER, AMINO-MERCAPTO TRIAZOLE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-09-24 US disclosed