SCHEMBL19640293

SCHEMBL19640293

c1cc2[nH]nnc2cc1-c1ccc2[nH]nnc2c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLK1 P49759 2/20 0.34
DYRK3 O43781 1/20 0.34
CLK2 P49760 1/20 0.34
CLK3 P49761 1/20 0.34
GSK3B P49841 1/20 0.34
CDK5 Q00535 1/20 0.34
DYRK1A Q13627 1/20 0.34
CDK5R1 Q15078 1/20 0.34
DYRK2 Q92630 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
DYRK1B Q9Y463 1/20 0.34
JAK2 O60674 3/20 0.33
CD40 P25942 1/20 0.33
CD40LG P29965 1/20 0.33
PIM1 P11309 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
QPCT Q16769 1/20 0.32
QPCTL Q9NXS2 1/20 0.32
MKNK1 Q9BUB5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23348984 0.98 CLK1 (0.37) CLK1DYRK3CLK2CLK3GSK3B
SCHEMBL366171 0.90 CLK2 (0.49) CLK1DYRK3CLK2CLK3GSK3B
SCHEMBL18608304 0.88 SMN1; SMN2 (0.37) GSK3BCDK5CDK5R1PIM1PIM3
Bicarbonate SCHEMBL8741996 0.84 GSK3B (0.44) CLK1DYRK3CLK2CLK3GSK3B
SCHEMBL24024580 0.84 PRKAG1 (0.47) DYRK1A
SCHEMBL28426471 0.78 QPCT (0.51) QPCTQPCTL
SCHEMBL24418021 0.78 TNIK (0.42) CLK1DYRK3CLK2GSK3BCDK5
SCHEMBL103309 0.77 CYP1A2 (0.39) PIM1
SCHEMBL7261306 0.77
SCHEMBL171634 0.77 NOS1 (0.44) CD40CD40LG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642570-A2 ACID GAS CAPTURE THROUGH METAL-LIGAND INSERTION IN POROUS MATERIALS AT ELEVATED TEMPERATURES The Regents of the University of California (US) 2025-11-05 EP claimed
WO-2024145655-A2 ACID GAS CAPTURE THROUGH METAL-LIGAND INSERTION IN POROUS MATERIALS AT ELEVATED TEMPERATURES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-04 WO claimed
US-11077398-B2 Compositions comprising metal organic frameworks for the uptake of compounds and related methods MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-08-03 US claimed
US-20200330918-A1 COMPOSITIONS COMPRISING METAL ORGANIC FRAMEWORKS FOR THE UPTAKE OF COMPOUNDS AND RELATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-10-22 US claimed
EP-3463655-A1 COMPOSITIONS COMPRISING METAL ORGANIC FRAMEWORKS FOR THE UPTAKE OF COMPOUNDS AND RELATED METHODS Massachusetts Institute Of Technology (US) 2019-04-10 EP claimed
US-20170341010-A1 COMPOSITIONS COMPRISING METAL ORGANIC FRAMEWORKS FOR THE UPTAKE OF COMPOUNDS AND RELATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-11-30 US claimed
WO-2017205752-A1 COMPOSITIONS COMPRISING METAL ORGANIC FRAMEWORKS FOR THE UPTAKE OF COMPOUNDS AND RELATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-11-30 WO claimed
US-20260131275-A1 SYSTEM AND METHOD FOR TARGETED GAS DESORPTION FROM SORBENTS VIA AN EDUCTOR PUMP MECHANISM MOSAIC MAT INC (US) 2026-05-14 US disclosed
EP-4642570-A2 ACID GAS CAPTURE THROUGH METAL-LIGAND INSERTION IN POROUS MATERIALS AT ELEVATED TEMPERATURES The Regents of the University of California (US) 2025-11-05 EP disclosed
WO-2024263243-A2 SORBENTS FOR THE TUNABLE CAPTURE AND RELEASE OF WATER AND RELATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-12-26 WO disclosed
WO-2024145655-A2 ACID GAS CAPTURE THROUGH METAL-LIGAND INSERTION IN POROUS MATERIALS AT ELEVATED TEMPERATURES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-04 WO disclosed
CN-117105586-A Nano enzyme carbonized product, preparation method and application thereof 山东汉博昱洲新材料有限公司 2023-11-24 CN disclosed
US-11643398-B2 Metallic salt containing anion having heterocyclic aromatic structure, method of preparing the metallic salt, and electrolyte and electrochemical device each including the metallic salt SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-05-09 US disclosed
EP-3463655-A1 COMPOSITIONS COMPRISING METAL ORGANIC FRAMEWORKS FOR THE UPTAKE OF COMPOUNDS AND RELATED METHODS Massachusetts Institute Of Technology (US) 2019-04-10 EP disclosed
US-20180250664-A1 COMPOSITIONS AND METHODS FOR SELECTIVE OLEFIN OLIGOMERIZATION COMPRISING METAL ORGANIC FRAMEWORKS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-09-06 US disclosed
US-20170341010-A1 COMPOSITIONS COMPRISING METAL ORGANIC FRAMEWORKS FOR THE UPTAKE OF COMPOUNDS AND RELATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-11-30 US disclosed
WO-2017205752-A1 COMPOSITIONS COMPRISING METAL ORGANIC FRAMEWORKS FOR THE UPTAKE OF COMPOUNDS AND RELATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-11-30 WO disclosed
WO-2017205752-A1 COMPOSITIONS COMPRISING METAL ORGANIC FRAMEWORKS FOR THE UPTAKE OF COMPOUNDS AND RELATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-11-30 WO disclosed
US-20170341010-A1 COMPOSITIONS COMPRISING METAL ORGANIC FRAMEWORKS FOR THE UPTAKE OF COMPOUNDS AND RELATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-11-30 US disclosed
US-20170341010-A1 COMPOSITIONS COMPRISING METAL ORGANIC FRAMEWORKS FOR THE UPTAKE OF COMPOUNDS AND RELATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170341010-A1 COMPOSITIONS COMPRISING METAL ORGANIC FRAMEWORKS FOR THE UPTAKE OF COMPOUNDS AND RELATED METHODS SLCO4C1, SLCO1A2, SLC10A6 CLK1 4118/4885DYRK3 3932/4885CLK2 4160/4885
US-20260131275-A1 SYSTEM AND METHOD FOR TARGETED GAS DESORPTION FROM SORBENTS VIA AN EDUCTOR PUMP MECHANISM EXOSC9, EXOSC4, EXOSC5 CLK1 755/4885DYRK3 281/4885CLK2 1560/4885
US-11077398-B2 Compositions comprising metal organic frameworks for the uptake of compounds and related methods SLCO4C1, SLCO1A2, SLC10A6 CLK1 4118/4885DYRK3 3932/4885CLK2 4160/4885
US-20200330918-A1 COMPOSITIONS COMPRISING METAL ORGANIC FRAMEWORKS FOR THE UPTAKE OF COMPOUNDS AND RELATED METHODS SLCO4C1, SLCO1A2, SLC10A6 CLK1 4118/4885DYRK3 3932/4885CLK2 4160/4885
US-11643398-B2 Metallic salt containing anion having heterocyclic aromatic structure, method of preparing the metallic salt, and electrolyte and electrochemical device each including the metallic salt NAP1L1, AGTR1, AP2A1 CLK1 2557/4885DYRK3 3947/4885CLK2 2246/4885
US-20180250664-A1 COMPOSITIONS AND METHODS FOR SELECTIVE OLEFIN OLIGOMERIZATION COMPRISING METAL ORGANIC FRAMEWORKS OSTC, NOD2, OCIAD2 CLK1 4077/4885DYRK3 3759/4885CLK2 3953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.