Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772588 | 0.85 | PTGDR (0.39) | FDFT1KDM4EALDH1A1PTGDRPTGDR2 | |
| SCHEMBL8423284 | 0.84 | FDFT1 (0.41) | FDFT1KDM4EALDH1A1PTGDRPTGDR2 | |
| SCHEMBL8772553 | 0.83 | MEN1 (0.39) | FDFT1KDM4EALDH1A1PTGDRPTGDR2 | |
| Hydrochloric Acid SCHEMBL8772602 | 0.82 | FDFT1 (0.42) | FDFT1ALDH1A1PTGDRPTGDR2MAPT | |
| Hydrochloric Acid SCHEMBL8421585 | 0.82 | FDFT1 (0.41) | FDFT1KDM4EPTGDRPTGDR2CHRM2 | |
| SCHEMBL8421714 | 0.82 | MAPT (0.42) | FDFT1KDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL8772595 | 0.81 | FDFT1 (0.38) | FDFT1KDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL8772704 | 0.81 | FDFT1 (0.37) | FDFT1PTGDRPTGDR2CHRM2CHRM4 | |
| SCHEMBL8772725 | 0.81 | ALDH1A1 (0.46) | KDM4EALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL8421904 | 0.81 | MAPT (0.42) | FDFT1KDM4EALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |