Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.57 |
| ▸ | TYMS | P04818 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420220 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TDP1ENPEPTYMSLMNA | |
| SCHEMBL3361351 | 0.93 | ALDH1A1 (0.87) | ALDH1A1TDP1ENPEPTYMSLMNA | |
| SCHEMBL744199 | 0.85 | — | — | |
| SCHEMBL6887604 | 0.82 | ALDH1A1 (0.70) | ALDH1A1TDP1ENPEPTYMSLMNA | |
| SCHEMBL16884463 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TDP1ENPEPTYMSLMNA | |
| SCHEMBL2849961 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TDP1ENPEPTYMSLMNA | |
| SCHEMBL700557 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TDP1ENPEPTYMSLMNA | |
| SCHEMBL1818974 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TDP1ENPEPTYMSLMNA | |
| SCHEMBL10879019 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TDP1ENPEPTYMSLMNA | |
| SCHEMBL3422061 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TDP1ENPEPTYMSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110267966-A | Oxysterol and methods of use thereof | 萨奇治疗股份有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-110072874-A | Oxysterol and methods of use thereof | 萨奇治疗股份有限公司 | 2019-07-30 | — | — | CN | disclosed |
| US-5869668-A | Processes for preparing L!- or D!-homoalanin-4-yl-(methyl) phosphinic acid and salts thereof by racemate resolution | HOECHST SCHERING AGREVO GMBH (DE) | 1999-02-09 | — | — | US | disclosed |
| US-5767309-A | PRECIPITATION OF ONE DISTEREOISOMERS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-06-16 | — | — | US | disclosed |
| EP-0499376-A1 | Precipitation-induced asymmetric transformation of chiral alpha-amino acids and salts thereof | HOECHST CELANESE CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |